Diabetes Mellitus, Type 2
Conditions
Interventions
This is a randomized, double-blind clinical trial aimed at evaluating the effect of adjunctive antimicrobial therapy with amoxicillin and metronidazole to non-surgical periodontal treatment in individ
Sponsors
Universidade Federal De Minas Gerais
Universidade Federal De Minas Gerais
Eligibility
Age
30 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with type 2 diabetes mellitus and stage II or III periodontitis; patients without diabetes; aged 30 years or older; of both sexes; with a minimum of fourteen teeth; who agree to participate in the research by signing an informed consent form (ICF)
Exclusion criteria
Exclusion criteria: Individuals with diseases that affect the immune system; smokers; pregnant or breastfeeding women; individuals allergic to amoxicillin or metronidazole; individuals who have undergone periodontal treatment in the last 6 months; individuals who have received antimicrobial or anti-inflammatory therapy in the last 3 months; individuals who change their diabetes medication during the study period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A reduction in probing depth is expected, verified through manual probing, based on an observed variation of at least 1 mm between pre- and post-intervention measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| A reduction in the percentage of sites with bleeding on probing is expected, verified through manual probing, based on the observed variation between pre- and post-intervention measurements. | — |
Countries
Brazil
Contacts
Public ContactRafael Lima
Universidade Federal De Minas Gerais
Outcome results
None listed