Effect of vitamin D3 supplementation on viral load and recovery of TCD4 + cells in HIV patients on antiretroviral therapy assisted by SUS

Effect of vitamin D3 supplementation on viral load and recovery of TCD4 + cells in HIV patients on antiretroviral therapy assisted by SUS - : SIDA

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

REBEC

Registry ID

RBR-5h432f

Enrollment

Unknown

Registered

2020-09-17

Start date

2017-08-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV-1

Interventions

Experimental group

65 people with HIV with or without antiretroviral treatment received vitamin D supplementation (50,000 IU and 8,000 IU) Control group: 65 people with HIV with or without antiretroviral treatment recei

Dietary supplement

D04.210.500.247.222.159

Eligibility

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: being under treatment in Teresina; being aged 20 years; never having used ART; who are not using vitamin or mineral supplementation; who do not have a diagnosis of metabolic diseases, diabetes, metabolic syndrome, thyroid disorders, bone diseases being treated, chronic renal failure, liver disease, gastric diseases or disabsorptive syndromes, neoplasms; pregnant and lactating women.

Exclusion criteria

Exclusion criteria: not complying with the proposed antiretroviral regimen or the placebo, supplement intake regimen during the six-month follow-up; pregnancy during follow-up; diagnosis of metabolic diseases, bone diseases being treated, chronic renal failure, liver disease, gastric diseases or disabsorptive syndromes, neoplasms during follow-up.

Design outcomes

Primary

Measure	Time frame
Presentation of the expected outcome (Analyze the effect of vitamin D3 supplementation on viral load and levels of CD4 cells in HIV-infected individuals using antiretroviral therapy (ART), assisted by the Unified Health System (SUS) in Teresina-PI and expected levels of TCD4+ cells to increase)	—

Secondary

Measure	Time frame
Presentation of the expected outcome (Analyze the effect of vitamin D supplementation on viral load and TCD4 cell levels in HIV-infected individuals using antiretroviral therapy (ART), assisted by the Unified Health System (SUS) in Teresina-PI and expected not to find that the levels of TCD4+ cells increase)	—

Countries

Brazil

Contacts

Public ContactAdriana;Adriana Paiva;Paiva

Universidade Federal do Piaui ;Universidade Federal do Piaui

aapaiva@ufpi.edu.com.br;aapaiva@ufpi.edu.com.br(86) 32155863;(86) 32155863

Outcome results

None listed

Source: REBEC (via WHO ICTRP)