Pulmonary Disease, Chronic Obstructive
Conditions
Interventions
This is a prospective, randomized feasibility trial with two parallel groups, conducted in a blinded manner for participants and outcome assessors. The sample consists of 30 participants diagnosed wit
the researcher responsible for administering the interventions is not blinded but is instructed not to disclose allocation information. The intervention group will consist of 15 participants and will
Sponsors
Hospital de Messejana Dr. Carlos Alberto Studart Gomes
Hospital de Messejana Dr. Carlos Alberto Studart Gomes
Eligibility
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Chronic obstructive pulmonary disease with moderate to severe airflow obstruction; minimum age of 40 years; of both sexes; on optimized pulmonary medication; clinically stable, with no history of disease exacerbation in the past month; classification on the modified Medical Research Council dyspnea scale less than or equal to 2; not having participated in a supervised and structured physical exercise program at least twice per week for at least 6 weeks within the past 6 months
Exclusion criteria
Exclusion criteria: Participants presenting any clinical condition that may contraindicate or compromise the proposed assessments or the use of blood flow restriction training, such as Peripheral Arterial Occlusive Disease; Deep Vein Thrombosis; Severe Peripheral Neuropathy; Coagulation Disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to assess the feasibility of recruitment and retention through the number of potentially eligible participants, as well as recruitment and retention rates.;To assess treatment acceptance and adherence through acceptance rates and adherence to the allocated intervention.;To evaluate outcomes based on the amount of missing data for essential outcome measures at each assessment point, such as health status, functional exercise capacity, and quadriceps strength.;It is expected to ensure the blinding of participants and outcome assessors through the identification of blinded participants during post-intervention assessments and blinded assessors at all evaluation points.;To assess the occurrence of intervention related adverse events during each training day through an adverse event checklist applied at the end of each training session. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess body structures through the cross-sectional area of the quadriceps femoris using a portable ultrasound device.;It is expected to assess body functions such as dyspnea using the modified version of the Medical Research Council scale, quadriceps strength through the maximum voluntary contraction test, and quadriceps endurance through the one-repetition maximum test.;To assess activities related to functional exercise capacity through the six-minute walk test.;To assess activity and participation through health-related quality of life/health status using the Saint George’s Respiratory Questionnaire and the Chronic obstructive pulmonary disease assessment test. | — |
Countries
Brazil
Contacts
Public ContactAndressa Souza
Hospital de Messejana Dr. Carlos Alberto Studart Gomes
Outcome results
None listed