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Association between brain and heart pressure

Association between Intracranial Pressure Compliance and parameters of central and peripheral arterial pressure and hemodynamics

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-5h33pjp
Enrollment
Unknown
Registered
2024-03-19
Start date
2022-11-11
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prehypertension

Interventions

This is an analytical, multicenter cross-sectional study whose primary outcome will be intracranial compliance in patients with different levels of blood pressure. Total sample of 500 patients. The an
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Sponsors

Faculdade de Medicina da Universidade Federal de Goiás
Lead Sponsor
Hospital das Clínicas da Universidade Federal de Goiás
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Subjects will be over 18 years of age; pre-hypertensive (arterial pressure sistolic between 130 and 139 mmHg and/or arterial pressure diastolic between 85 and 89 mmHg) or hypertensive (arterial pressure sistolic higher than 140 mmHg and/or arterial pressure diastolic lower than 90 mmHg) according to office blood pressure measurement

Exclusion criteria

Exclusion criteria: Patients taking blood pressure medication; with stage 3 hypertension (arterial pressure sistolic higher than 180 mmHg and/or arterial pressure diastolic higher than 110 mmHg); pregnant or puerperal women; patients diagnosed with intracranial hypertension; patients with hydrocephalus, previous cardiovascular disease which will be defined as: history of coronary heart disease (angina, previous heart attact), diagnosis of Heart Failure, history of valvular heart disease, diagnosis of cardiac arrhythmias, obstructive peripheral arterial disease, aortic aneurysm, previous stroke and advanced chronic liver disease (Child B and C)

Design outcomes

Primary

MeasureTime frame
We expect to find the value of the P2/P1 ratio greater than 1.2 and the value of the Time to peak (TTP) greater than 0.20 s

Secondary

MeasureTime frame
No secondary outcomes expected

Countries

Brazil

Contacts

Public ContactWeimar de Souza

Faculdade de Medicina da Universidade Federal de Goiás

sebbabarroso@gmail.com+55 (62) 99416-4280

Outcome results

None listed

Source: REBEC (via WHO ICTRP)