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Effects of a Walking Program associated with Blood Flow Restriction on strength, muscle thickness, and gait in individuals with leg strength imbalance

Effects of a Walking Program associated with Partial Blood Flow Restriction on muscular and functional aspects in individuals with muscle strength asymmetry in lower limbs

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5gqgs99
Enrollment
Unknown
Registered
2024-11-06
Start date
2024-11-20
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gait

Interventions

This study will be experimental with a non-randomized clinical trial design. An initial screening will be conducted to identify individuals with inter-limb strength asymmetry in the knee extensor musc

Sponsors

Universidade Federal do Paraná
Lead Sponsor
Universidade Federal do Paraná
Collaborator

Eligibility

Age
18 Years to 59 Years

Inclusion criteria

Inclusion criteria: Individuals aged between 18 and 59 years; muscle strength difference between lower limbs greater than or equal to 10 per cent in the knee extensor musculature (quadriceps), indicating asymmetry; medical clearance for training, granted by the physician associated with the study (Dr. Francisco Wekerlin Morozowski); signing the Informed Consent Form; completing 75 per cent of the proposed training sessions if selected for the intervention

Exclusion criteria

Exclusion criteria: Having conditions that prevent the completion of questionnaires, understanding of instructions, and performance of tests (e.g., severe vestibular deficits, mobility deficits, and cognitive impairment); having systolic blood pressure greater than or equal to 140 mmHg or diastolic blood pressure greater than or equal to 90 mmHg; having more than one risk factor for thromboembolism, which includes: body mass index greater than or equal to 30 kg/m². diagnosis of chronic inflammatory disease. history of pelvic, hip, and femur fractures. major surgeries in the last 6 months. diagnosis of varicose veins in the last 6 months. family history of deep vein thrombosis and pulmonary embolism. use of oral contraceptives. tobacco use

Design outcomes

Primary

MeasureTime frame
A significant increase in muscle strength (peak torque, N.m) is expected, verified using the Biodex Multi-joint System Dynamometer (Biodex Medical Systems, Inc., Shirley, NY, USA) by comparing the pre- and post-intervention (12 weeks) measurements.

Secondary

MeasureTime frame
A significant reduction in the inter-limb strength asymmetry of the knee extensor musculature, identified in the initial assessment, is expected. This will be verified using the Biodex Multi-joint System Dynamometer (Biodex Medical Systems, Inc., Shirley, NY, USA) by comparing the pre- and post-intervention (12 weeks) measurements.;A significant increase in muscle thickness (cm) is expected, verified using the portable B-mode ultrasound device Version 1.10 (Konica Minolta, model Sonimage HS1) by comparing the pre- and post-intervention (12 weeks) measurements.;A significant improvement in gait performance is expected, evaluated through spatiotemporal and variability parameters at different walking speeds (self-selected and fast walking speed). Gait parameters will be assessed and analyzed using an instrumented walkway, the Zeno Walkway (120Hz), and the ProtoKinetics Movement Analysis Software, by comparing the pre- and post-intervention (12 weeks) measurements.

Countries

Brazil

Contacts

Public ContactLetícia da Silva

Universidade Federal do Paraná

leticiapophal@hotmail.com+55 41 3361-3072

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Apr 15, 2026