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Evaluation of the Types of Hydration Solutions Used in Renal Transplantation

Impact of the Crystalloid Solutions on the occurrence of Acidosis and Hyperkalaemia in Renal Transplantation: Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5fzq2w7
Enrollment
Unknown
Registered
2023-06-05
Start date
2020-12-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Failure, Chronic

Interventions

The intervention will be about the types of hydration solutions used during kidney transplantation. Recruited patients will be randomized into three groups, each containing 15 participants. The saline

Sponsors

Hospital Universitário Onofre Lopes
Lead Sponsor
Hospital Universitário Onofre Lopes
Collaborator

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients submitted to renal transplantation in Hospital Universitário Onofre Lopes

Exclusion criteria

Exclusion criteria: Patient refusal;Patients younger than 18 years; patients with preoperative serum potassium greater than 5.5 mEq / L; additional surgery to the renal transplant in the same surgical time; intraoperative complications requiring additional volume expansion (eg bleeding)

Design outcomes

Primary

MeasureTime frame
Evaluate the occurrence of acidosis (pH less than 7.2) intraoperatively and postoperatively (first 72 hours) of kidney transplantation, assessed by venous gasometry.;Evaluate the occurrence of hyperkalemia (k greater than 5.0 meq/L) intraoperatively and postoperatively (first 72 hours) of kidney transplantation, assessed by venous blood gas analysis. Note: both acidosis and hyperkalemia were used for sample calculation.

Secondary

MeasureTime frame
The need for early postoperative hemodialysis (first 24 hours); The hemodialysis criteria are: anuria, acidosis, hyperkalaemia and hypervolemia. ;The need for non-dialytic treatment of acidosis (ph less than 7,2) and hyperkalaemia (k more than 5,0 meq/L) in the intraoperative and postoperative periods.;Postoperative graft function through urinary output and postoperative creatinine (up to 72 hours).;To compare the occurrence of intraoperative and postoperative coagulation disorders, mensuared by prothrombin time and partial thromboplastin time.

Countries

Brazil

Contacts

Public ContactWallace Da Silva

Hospital Universitário Onofre Lopes

wallaceandrino@yahoo.com.br+55 (84) 8106-7252

Outcome results

None listed

Source: REBEC (via WHO ICTRP)