Hepatic Encephalopathy
Conditions
Interventions
specific cause of liver disease
and comorbidities. Regarding the disease, the following will be recorded: type of liver disease
This is a prospective-analytical study of the diagnostic test type. Control group: 30 patients with liver disease without hepatic encephalopathy. Experimental group: 30 liver disease patients with pre
heart rate variability will be recorded with the Polar H10 heart rate monitor for 20 minutes
and the participants identification data and exposures described in the electronic medical record will be collected. Participants' descriptive data collected from the medical record will include: medi
full name
age
sex
previous CT scan with evidence of cerebral edema
whether there was invasive intracranial pressure monitoring
invasive intracranial pressure at the time of insertion
post-insertion maximal invasive intracranial pressure
monitoring days
occurrence of hemorrhage. Regarding the treatment, it will be collected: if there was a liver transplant
hyperosmolar treatment
and others. Regarding the laboratory tests of the participants, they will be tabulated, if any: maximum INR
and serum ammonia (minimum, maximum, average). Regarding the state of the participants liver disease, it will be reported: neurological symptoms classification according to neurological score. About t
Sponsors
Faculdade de Medicina de São José do Rio Preto - Famerp - SP
Brain4Care
Eligibility
Inclusion criteria
Inclusion criteria: Subjects with acute liver disease; subjects with chronic liver disease; subjects with exacerbation of chronic liver disease
Exclusion criteria
Exclusion criteria: Refusal by the subjects or their guardians to participate in the study; subjects with healthy liver
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Using the Brain4Care band, it is expected to find a correlation between non-invasive intracranial pressure data and a clinical picture compatible with hepatic encephalopathy | — |
Secondary
| Measure | Time frame |
|---|---|
| Using the Polar H10 cardiac monitor and the BWS system, it is expected to find a correlation between non-invasive intracranial pressure data, heart rate variability and the clinical status of hepatic encephalopathy | — |
Countries
Brazil
Contacts
Public ContactMoacir de Godoy
Faculdade de Medicina de São José do Rio Preto - Famerp - SP
Outcome results
None listed