Hematologic Neoplasms. Leukemia. Lymphoma. Squamous Cell Carcinoma of Head and Neck. Esophageal Neoplasms. Facial Neoplasms. Mouth Neoplasms. Parathyroid Neoplasms. Thyroid Neoplasms. Tracheal Neoplasms
Conditions
Interventions
This is a randomized, controlled, two-arm, single-blind clinical trial. Approximately 15 participants with hematologic cancer or head and neck cancer, ready to start chemotherapy, will receive the nut
Sponsors
Universidade Federal de Santa Catarina
Hospital Universitário Polydoro Ernani de São Thiago
Eligibility
Age
19 Years to No maximum
Inclusion criteria
Inclusion criteria: individuals aged 19 years or over; both sexes; with recent clinical diagnosis of hematologic cancer or head and neck cancer and with indication to start chemotherapy treatment; in conditions of oral ingestion.
Exclusion criteria
Exclusion criteria: in palliative care; using statins and/or other anti-inflammatory drugs; who have undergone anticancer treatment in the 5 years prior to the survey; diagnosed with infectious contagious diseases; with indication for the use of enteral or parenteral nutrition; who have taken dietary supplements in the 6 months prior to the study; and who have an intolerance or allergy to any component of the adapted ice cream. Pregnant and lactating women will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maintenance and/or improvement of nutritional status, assessed through body composition by bioelectrical impedance with phase angle on the 1st day of chemotherapy and on the 21st day after the start of chemotherapy (in the pilot study) or 9th week. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence, duration and severity of oral mucositis, evaluated through clinical examination by a dental professional following the World Health Organization classification parameters for oral mucositis severity.;Changes in inflammatory and oxidative stress markers, assessed by taking blood from participants on day 1 of chemotherapy and on day 21 after chemotherapy initiation (in the pilot study) or week 9.;Changes in the Quality of Life pattern, assessed through the application of a structured and validated questionnaire for this population, on the 1st day of chemotherapy and on the 21st day after the start of chemotherapy (in the pilot study) or 9th week. | — |
Countries
Brazil
Contacts
Public ContactBetina;Francilene Dambrós;Kunradi Vieira
Universidade Federal de Santa Catarina;Universidade Federal de Santa Catarina
Outcome results
None listed