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The use of Vitamin C and Magnesium to help with teeth alignment

Use of Vitamin C and Magnesium in induced tooth movement

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5drmd88
Enrollment
Unknown
Registered
2025-11-10
Start date
2024-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malocclusion

Interventions

This is a two-arm, randomized controlled clinical trial with random allocation of 20 participants (10 in each group), including youths and adults aged 15 years and older, proportionally distributed ac

Sponsors

Fundação Universidade Federal de São João del Rei Campus Centro Oeste Dona Lindu
Lead Sponsor
Universidade Federal de São João Del Rei - Campus Centro Oeste Dona Lindu
Collaborator

Eligibility

Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: Population of both sexes, adults and adolescents from 15 years of age, treated at the dental clinic belonging to the university of Itaúna. Individuals undergoing orthodontic treatment with metal brackets and retraction of incisors and canines, submitted to sliding mechanics, to close the space created by the therapeutic extraction classically recommended in the reduction of the facial profile

Exclusion criteria

Exclusion criteria: Smokers; Pregnant or breastfeeding women; Individuals with systemic diseases, such as diabetes, under drug therapy with antiepileptics (phenytoin), calcium channel blockers (nifedipine) and immunosuppressants (cyclosporine); Individuals using antimicrobial or anti-inflammatory drugs; Individuals with a history of scaling and root planing in the last 3 months; Individuals with significant tooth mobility, proven in the clinical examination; Individuals with poor oral hygiene; Individuals without minimum autonomy (due to mental or consciousness changes), according to the interviewer's subjective assessment. Individuals with fistula or pain of endodontic origin

Design outcomes

Primary

MeasureTime frame
To evaluate a formulation containing vitamin C associated with magnesium in volunteers undergoing orthodontic treatment to increase movement speed and periodontal health

Secondary

MeasureTime frame
To compare the rate of tooth movement after 60 days of dental retraction between individuals with and without vitamin C and magnesium supplementation;To evaluate the influence of vitamin C and magnesium supplementation on periodontal health following 60 days of dental retraction;Evaluate the occurrence of systemic effects;Evaluate the occurrence of adverse effects in the treatment

Countries

Brazil

Contacts

Public ContactMarcos Carvalho

Universidade Federal de São João Del Rei - Campus Centro Oeste Dona Lindu

marcoscarvalhoorto@gmail.com+55(31)99246-0534

Outcome results

None listed

Source: REBEC (via WHO ICTRP)