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Could trained people have a better response of the defense mechanisms in the presence of the COVID-19 virus than sedentary people? A follow-up study to monitor the Immune System and Stiffness of the Arteries

Could physical fitness level modulate innate immune response and prevent Arterial Stiffening and Vascular Dysfunction in COVID-19 patients?A follow-up study for monitoring of Immune Function and Arterial Stifffness

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-5dqvkv3
Enrollment
Unknown
Registered
2021-09-21
Start date
2021-05-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronavirus Infections

Interventions

A prospective study will be performed during ± 18 months. A Cohort including participants previously infected with the SARS-CoV-2 (Group 1) and age-matched healthy participants (Group 2) will be arran

Sponsors

Universidade Estadual Paulista Julio de Mesquita Filho
Lead Sponsor
Universidade de São Paulo
Collaborator

Eligibility

Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients with previous SARS-CoV-2 infection; mild signs of COVID-19; show positive PCR test for covid 19; both genders; aged between 20 and 40 years old.

Exclusion criteria

Exclusion criteria: presence of chronic non-communicable diseases; drug use; use of anti-inflammatory drugs; use of antibiotics; frequent alcohol consumers; smokers

Design outcomes

Primary

MeasureTime frame
To observe the modulating effect of lifestyle on the organic response to SARS-CoV-2 infection across a broad spectrum of physiological and molecular-level variables. The research will highlight the importance of physical activity and body composition in the natural history of COVID-19 in relation to specific vaccination, adding evidence on the cumulative effects of physical activity on antiviral immune processes and cardiovascular and mental health.

Secondary

MeasureTime frame
Secondary outcomes are not expected.

Countries

Brazil

Contacts

Public ContactFabio Lira
fabio.lira@unesp.br+55-018-32295826

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 13, 2026