Stroke, paresis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Right or left hemiparesis, with at least six months of the occurrence of stroke; be able to walk without supervision for home walking; enrolled in a neuro-motor rehabilitation program; score above 36 on the Berg balance scale; minimum score of 50 on the Fulg-Meyer scales; signature of the written informed consent form.
Exclusion criteria
Exclusion criteria: Smoking; history of drug or alcohol abuse; using beta-blockers, neuroleptics or medications that alter the threshold excitement of the neuronal membrane; hormone replacement therapy; head trauma; metallic prosthetic device in the skull; evidence of secondary hypertension; diagnosed with metabolic, liver, cardiac, oncological, psychiatric, neurological pathologies; body mass index 35 kg / m2. g) Estimated glomerular filtration rate 3x upper reference value; i) Patients with clinical evidence of coronary disease with a history of angina or tests compatible with myocardial ischemia; j) Previous history of acute myocardial infarction and/or myocardial revascularization; k) Clinical signs of heart failure, symptomatic cardiac arrhythmia or clinically significant valve disease; l) Patients with a history of drug or alcohol abuse in the last 10 years; m) Patients with a history of cancer in the last five years; n) History of neurological or psychiatric disease (e.g. epilepsy); o) History of cranial trauma at any age or existence of a metal prosthetic device or other metal particle in the skull.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brachial blood pressure: Measurement performed in millimeters of mercury (mmHg), for 10 minutes pre-intervention and for 40 minutes after the intervention, in the laboratory, using photoplethysmography (Finometer, Finapress TM). And for 24 hours after the intervention through ambulatory blood pressure monitoring (Spacelabs TM). | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate variability: laboratory measurement performed in milliseconds, for 10 minutes before the intervention, during the entire intervention and for 40 minutes after the intervention (V800, Polar TM). Measurement performed for 24 hours after the intervention, by Holter recorder (CardioLight, Cardios TM).;Ventilatory exchange: Performed by indirect calorimetry for 10 minutes before the intervention, during the entire intervention and for 40 minutes after the intervention, measuring oxygen consumption, carbon dioxide production and ventilation in liters per minute.;Arterial function: Performed using piezoelectric transducers before and 40 minutes after the intervention, measuring the pulse wave velocity (meters per second), arterial compliance (10 to power of six centimeters to the power of 5 per dyna) and the reflection index of the pulse wave (percentage).;Affectivity: Measured by scales that evaluate pleasure (Feeling Scale: scores between -5 and +5) and arousal (Felt Arousal Scale - scores between 1 and 6) before and after the intervention. | — |
Countries
Brazil
Contacts
Universidade do Estado do Rio de Janeiro;Universidade do Estado do Rio de Janeiro