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Evaluation of the effects of a single dose of Cannabidiol on attention and memory in people with Obsessive Compulsive Disorder

Analysis of the effects of Acute Cannabidiol Administration on Attention and Memory Bias in Patients with Obsessive Compulsive Disorder

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5dbqvhd
Enrollment
Unknown
Registered
2024-03-04
Start date
2023-09-23
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-compulsive disorder

Interventions

This is a double-blind, placebo-controlled randomized clinical trial. Experimental group: 17 patients of both sexes diagnosed with obsessive-compulsive disorder will receive a single dose of cannabidi
D02.455.849.090
HP3.073.433

Sponsors

Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Lead Sponsor
Hospital das Clínicas da Faculdade de Medina de Ribeirão Preto da Universidade de São Paulo
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Intervention Group: 17 patients diagnosed with Obsessive Compulsive Disorder will be included according to the diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders, 5th edition, revised text (DSM-5-TR); of both sexes; aged 18 or over; and who do not have any other psychiatric comorbidity Control Group: 17 subjects will be included without any current or previous psychiatric disorder; of both sexes; and who are 18 years of age or older

Exclusion criteria

Exclusion criteria: Intervention Group: Patients who present adverse reactions to the use of the substance or those who do not complete the experimental tasks that make up the study will be excluded. Control Group: Subjects who present adverse reactions to the use of the substance or those who do not complete the experimental tasks that make up the study will be excluded.

Design outcomes

Primary

MeasureTime frame
Reduction and/or elimination of attention bias and implicit memory that will be assessed using the Emotional Stroop, Dot Probe and Implicit Association Test instruments, all three instruments were personalized for Obsessive Compulsive Disorder.—

Secondary

MeasureTime frame
Decrease in anxiety and other aspects of mood, assessed using the Analog Mood Scale (VAMS), and the presence or absence of side effects, assessed using the Society's Clinical Investigation Committee's Scale for Side Effects of Psychotropic Drugs Scandinavian Institute of Psychopharmacology (UKU).—

Countries

Brazil

Contacts

Public ContactAdrieli Raminelli

Faculdade de Medicina de Ribeirão Preto

adrieliraminelli@usp.br+55(16)981774687

Outcome results

None listed

Source: REBEC (via WHO ICTRP)