Spinal cord injury
Conditions
Interventions
Twenty volunteers will be included in the study, which will be divided into two groups: Group 1: Control Group / Intensive Training Group (GTI
n = 10), and will be part of this group individuals who already perform intensive training of neurofunctional rehabilitation at least 6 months and will be submitted to a single walking training sessio
n = 10): this group will be individuals who undergo conventional physiotherapy and will be submitted to a single walking training session with SPC on a treadmill. After an interval of at least 48 hour
Other
G11.427.410.698.277
E02.760.169.063.500.387
Sponsors
Centro Universitário Metodista-IPA
Centro Universitário Metodista-IPA
Eligibility
Age
17 Years to 55 Years
Inclusion criteria
Inclusion criteria: For both groups, individuals with incomplete traumatic LM; aged between seventeen and fifty-five years old; of both genders and diagnosed for at least 6 months and at most 5 years of injury, will be included. For the trained groups, the subjects should be submitted to an intervention program (neurofunctional rehabilitation) for at least 6 months. For untrained groups, individuals should be performing only conventional physiotherapy.
Exclusion criteria
Exclusion criteria: As exclusion criteria, for both groups, all those with contraindications to weight support, such as individuals with hip fracture or lower limb or who present scabs, are included. Also, patients who present with unstable angina or other decompensated heart disease; chronic obstructive pulmonary disease; neurological diseases such as Parkinson's; stroke; who exhibit symptomatic drop in blood pressure when upright; who use medications with HDAC inhibitors valproic acid) and are undergoing active inflammation / infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase of 50% on levels of histone acetylation and reduction of inflammatory markers and muscle injury after soil and treadmill intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Increase of 50% on electromyographic activity of the quadriceps muscle with the intervention. | — |
Countries
Brazil
Contacts
Public ContactViviane Elsner
Centro Universitário Metodista-IPA
Outcome results
None listed