Language Development Disorders
Conditions
Interventions
This is a non-randomized, single-arm, unblinded crossover clinical trial. Fifteen children who meet the eligibility criteria will be included. All participants will undergo two phases of general anest
Sponsors
Faculdade de Medicina da Universidade de São Paulo
Faculdade de Medicina da Universidade de São Paulo
Eligibility
Inclusion criteria
Inclusion criteria: Children under investigation for language delay or suspected autism spectrum disorder, or undergoing audiological monitoring, who are scheduled to undergo an auditory brainstem response under general anesthesia must present: transient otoacoustic emissions with at least four reproducible responses; distortion product otoacoustic emissions with at least four reproducible responses; and auditory brainstem responses demonstrating waves I, III, and V elicited by a click stimulus at 80 decibels
Exclusion criteria
Exclusion criteria: Suspected or confirmed genetic syndromes; american society of anesthesiologists physical status classification of three or higher; patients with middle ear pathology; non-portuguese speakers; clinical history of neurological disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the effect of sevoflurane versus propofol on auditory brainstem evoked potential parameters, evaluating absolute latencies of waves I, III, and V and their interpeak intervals during titrated anesthetic maintenance for adequate hypnosis | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected | — |
Countries
Brazil
Contacts
Public ContactRobinson Tsuji
Faculdade de Medicina da Universidade de São Paulo
Outcome results
None listed