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Analysis of 2 drug protocol of dexamethasone in the removal of wisdom tooth

Analysis of 2 preemptive periods of dexamethasone in the removal of the third molars. A controlled, randomized, split-mouth, and triple-blind clinical study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
REBEC
Registry ID
RBR-5bzbvs
Enrollment
Unknown
Registered
2020-07-30
Start date
2019-01-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Loss of teeth due to accident, extraction or local periodontal disease

Interventions

The medication was previously manipulated and stored in pills, so that the patient and the surgeon did not know to which group they belonged. Group 1 received a fractionated dose of dexamethasone, 1 p
Drug
Procedure/surgery
E06.892

Sponsors

Universidade Estudal Paulista
Lead Sponsor
Universidade Estadual Paulista
Collaborator

Eligibility

Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Young adult patient (18-30 years); Third bilateral molars (upper and lower) with similar positions and angulations evaluated in panoramic; Need for osteotomy and odontostomy for exodontia.

Exclusion criteria

Exclusion criteria: Smolker; Decompensated Metabolic Diseases; Use of medicines that interfere with healing; Periodontal Disease; Inflammation or pathologies associated with third molars.

Design outcomes

Primary

MeasureTime frame
Postoperative pain control, measured by visual analogic scale (<5), this is the major parameter.;Decreased the number of analgesic rescue, measured by number of analgesics used on postoperative time.

Secondary

MeasureTime frame
Low postoperative trismus(< 38mm and 15mm às 48 hours e 7-days, respectively); ;Postoperative edema (< 4.5mm and 2.5mm at 48hours and 7-days, respectively) measured by the metrics parameters.

Countries

Brazil

Contacts

Public ContactAnderson Santos

Universidade Estadual Paulista

ams.santos@unesp.br+55-018-36363237

Outcome results

None listed

Source: REBEC (via WHO ICTRP)