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Rating of ventilation with two pressure levels when the patient exhales in patients with severe inflammatory disease in the lung.

Short-term effects of mechanical ventilation with two levels of PEEP (BiPEEP) in patients with Acute Respiratory Distress Syndrome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5bb65v
Enrollment
Unknown
Registered
2016-03-03
Start date
2015-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome

Interventions

Randomized crossover clinical trial, which will be included patients with acute respiratory distress syndrome who are undergoing invasive mechanical ventilation later, they will be randomized to one o
Other
C02.782.600.550.200.750

Sponsors

Centro Universitário Metodista - IPA
Lead Sponsor
Complexo Hospitalar Santa Casa de Porto Alegre
Collaborator

Eligibility

Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Mechanically ventilated patients for more than 24 hours; presenting hemodynamically stable (mean arterial pressure between 70 and 120 mm Hg); PaO 2 / FiO 2 100-300; diffuse infiltrates on chest radiograph.

Exclusion criteria

Exclusion criteria: Patients with a history of pulmonary emphysema; presence of barotrauma; chest tube; undrained pneumothorax.

Design outcomes

Primary

MeasureTime frame
Increased blood oxygenation after 60 minutes period with the experimental ventilator checked by arterial blood gas from finding a variation of at least 10% in pre and post intervention measurements.—

Secondary

MeasureTime frame
Increased lung compliance after 60 minutes period with the experimental ventilator checked by arterial blood gases from the realization of a range of at least 15% in the pre and post intervention measurements.—

Countries

Brazil

Contacts

Public ContactLuiz Forgiarini Junior

Centro Universitário Metodista - IPA

forigiarini.luiz@gmail.com+55 (51) 9136.5047

Outcome results

None listed

Source: REBEC (via WHO ICTRP)