Diabetes Mellitus, Type 2
Conditions
Interventions
This is a randomized clinical trial, single-blind, that aims to evaluate the effects of two programs of water-based combined training on health parameters of adults with type 2 diabetes. The sample wi
G11.427.410.698.277
Sponsors
Universidade Federal do Rio Grande do Sul
Universidade Federal do Rio Grande do Sul
Eligibility
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: Men and women with type 2 diabetes mellitus; aged between 40 and 65 years; who are undergoing medical treatment using oral hypoglycemic agents and/or insulin; who are not practicing systematic physical exercise in the three months prior to the study
Exclusion criteria
Exclusion criteria: Uncontrolled hypertension; autonomic neuropathy; severe peripheral neuropathy; proliferative diabetic retinopathy; severe non-proliferative diabetic retinopathy; uncompensated heart failure; peripheral amputations; chronic renal failure; body mass index (BMI) > 45.0 kg/m2; individuals who experienced severe symptoms of COVID-19 in the previous 12 months (resulting in hospitalization); any muscle or joint impairment that prevents the performance of physical exercises safely
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find improvements in the blood levels of glycated hemoglobin (HbA1c). The collection of blood samples will be performed after a 12-hour fast. Blood concentration analyses will be evaluated by the colorimetric enzymatic method using a biochemical analyzer (Cobas C111 – Roche). The mean differences of the groups between pre- and post-training periods and between the two training groups will be analyzed. In addition, the 1% change will be used to assess clinically significant changes in individual responsiveness to training. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find improvements in the blood levels of fasting glucose. The collection of blood samples will be performed after a 12-hour fast. Blood concentration analyses will be evaluated by the colorimetric enzymatic method using a biochemical analyzer (Cobas C111 – Roche). The mean differences of the groups between pre- and post-training periods and between the two training groups will be analyzed.;It is expected to find improvements in the blood levels of triglycerides. The collection of blood samples will be performed after a 12-hour fast. Blood concentration analyses will be evaluated by the colorimetric enzymatic method using a biochemical analyzer (Cobas C111 – Roche). The mean differences of the groups between pre- and post-training periods and between the two training groups will be analyzed.;It is expected to find improvements in the blood levels of total cholesterol. The collection of blood samples will be performed after a 12-hour fast. Blood concentration analyses will be evaluated by the colorimetric enzymatic method using a biochemical analyzer (Cobas C111 – Roche). The mean differences of the groups between pre- and post-training periods and between the two training groups will be analyzed.;It is expected to find improvements in the blood levels of high-density lipoprotein (HDL). The collection of blood samples will be performed after a 12-hour fast. Blood concentration analyses will be evaluated by the colorimetric enzymatic method using a biochemical analyzer (Cobas C111 – Roche). The mean differences of the groups between pre- and post-training periods and between the two training groups will be analyzed.;It is expected to find improvements in the blood levels of C-reactive protein. The collection of blood samples will be performed after a 12-hour fast. Blood concentration analyses will be evaluated by the colorimetric enzymatic method using a biochemical analyzer (Cobas C111 – Roche). The mean differences of the groups between pre- and pos | — |
Countries
Brazil
Contacts
Public ContactLuiz Kruel
Universidade Federal do Rio Grande do Sul
Outcome results
None listed