Preschool children with inguinal hernia
Conditions
Interventions
Fifty four children were initially enrolled to participate in the study, and later 14 were excluded. The forty remaining children were randomly assigned into two groups:
Control group (fasting): 19 p
Dietary supplement
G07.203.300.456
Sponsors
Santa Casa de Misericórdia de Cuiabá
Santa Casa de Misericórdia de Cuiabá
Eligibility
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: The enrolled patients were children aged from 2 to 6 years; who were to be treated at the hospital Santa Casa of Misericórdia; presented an anesthetic risk classified as ASA I or II (healthy patient or small morbidity); and were to be operated for inguinal elective herniorrhaphy (small and moderate inguinal hernias).
Exclusion criteria
Exclusion criteria: Where excluded patients with other concomitant surgical diagnoses detected during hospitalization; as well as patients with giant inguinal hernias; those whose surgeries were cancelled due to respiratory symptoms; patients whose parents declined to participate in the study; with failure during collection of blood samples; who did not correctly followed the perioperative protocol delineated by the research where also excluded from the research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1 A reduction in preoperative fasting time is expected in CHO group patients ;Outcome found 1 There was a reduction in preoperative fasting time in CHO patients (2:29 vs 11:24, p smaller than 0.001) ;Expected outcome 2 A reduction in acute inflammatory function tests related to the organic response to surgical trauma (CRP) is expected in CHO group patients, during the perioperative period ;Outcome found 2 A reduction in CRP values was observed both preoperatively (fasting group: 3.60 ± 7.60 mg/L vs CHO group: 0.53 ± 0.59 mg/L; p equal to 0.05) and postoperatively (fasting group: 3.53 ± 7.75 mg/L vs CHO group: 0.49 ± 0.0 mg/L, p equal to 0.02) ;Expected outcome 3 It is expected that there will be a reduction in acute inflammatory function tests related to the organic response to surgical trauma (CRP/Albumin) in patients in the CHO group during the perioperative period. ;Expected found 3 There was a reduction in the values of the inflammatory test CRP/Albumin in the preoperative period (0.89 ± 1.86 vs 0.13 ± 0.15, p equal to 0.03) in the CHO group patients. In the postoperative period, there was no statistical difference between groups (0.91 ± 1.97 vs 0.13 ± 0.15, p equal to 0.08) ;Expected outcome 4 It is expected that there will be a reduction in acute inflammatory function tests related to the organic response to surgical trauma (Interleukin-6) in CHO patients during the perioperative period ;Expected found 4 There was no statistical difference between the two groups both pre (fasting: 1.5 ± 2.6 pg/ml vs CHO: 2.0 ± 1.3 pg/ml, p equal to 0.98) and postoperatively (fasting: 2.0 ± 2.3 pg/ml vs CHO: 1.5 ± 2.0, pg/ml, p equal to 0.41) ;Expected outcome 5 Better postoperative glucose metabolism is expected in CHO patients ;Expected found 5 There was no statistical difference between groups in preoperative (fasting: 88 ± 16 mg/dl vs CHO: 86 ± 9 mg/dl, p equal to 0.32) or postoperative blood glucose (fasting: 91 ± 34 mg/dl vs CHO: 93 ± 24 mg/dl, p equal | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 7 Associated with a reduction in the inflammatory response to trauma, a reduction in the occurrence of postoperative vomiting is expected Expected outcome 7 No difference was observed in the incidence of postoperative vomiting between the groups.;Expected outcome 7 In children which preoperative fasting was abbreviated, better degrees of parental satisfaction are expected Expected outcome 7 It was decided not to measure the degree of parental satisfaction due to the lack of an objective and easy measurement | — |
Countries
Brazil
Contacts
Public ContactCarlos Leite de Barros Carvalho
Santa Casa de Misericórdia de Cuiabá
Outcome results
None listed