Periapical Abscess, Dental Pulp Necrosis, Pain, Pain Measurement.
Conditions
Interventions
Anesthesia with 2% lidocaine, with epinephrine 1: 100,000. Under absolute isolation (where possible), opening of the pulp chamber followed by neutralization of septic-toxic content with K # 08, 10 or
Drug
Procedure/surgery
Sponsors
Faculdade de Odontologia da Universidade Federal do Rio Grande do Sul
Faculdade de Odontologia da Universidade Federal do Rio Grande do Sul
Eligibility
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients were included in this research according to the following criteria: individuals 18 to 80 years old; diagnosis of acute apical abscess with pulpar necrosis origin; reporting mod-erate to severe pain at the first appointment (equal or superior to 40mm on VAS).
Exclusion criteria
Exclusion criteria: They will be relieved to report being allergic to drugs not present, patients with a history of liver disease and infants. Patients with chronic and / or anti-inflammatory opiates were also excluded, those who were or are users of substances such as crack, oxy, cocaine, marijuana and solvents. In addition, patients with cognitive (and therefore according to scales) as well as patients with cognitive impairment (and therefore from afar).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| As a primary endpoint, the pain scores will be evaluated by means of visual analog scale (VAS) from patients with an acute dentoalveolar abscess.;The pain scores were evaluated by means of AVA of patients with an acute dentoalveolar abscess.In both groups, pain score reduction was observed over time. Significant differences were identified comparing the pain scores for 12, 24, 48, and 72 hours to the initial ones. Para-cetamol-codeine group revealed lower scores in 48 hours in relation to the initial and the 6 hours values, while 72 hours scores were lower than initial, 6 and 12 hours ones (P lower than 0,05). | — |
Secondary
| Measure | Time frame |
|---|---|
| As a secondary outcome, the frequency of adverse reactions eventually described by patients will be considered, carried out through questioning in appointment.;There was no statistical difference on adverse effects between groups (P lower than 0,05). Eleven (57,9%) patients from paracetamol group and twelve (60%) patients from paraceparace-tamol-codeine group demonstrated at least one adverse effect (dizziness, drowsiness, nausea, headache, vomiting or others). | — |
Countries
Brazil
Contacts
Public ContactMarcus Vínicius Só
Faculdade de Odontologia da Universidade Federal do Rio Grande do Sul
Outcome results
None listed