viral load
Conditions
Interventions
a) Experimental / Antiseptic group and active toothpaste: 20 patients will perform mouthwash / gargle for 1 minute (30s mouthwash / 30s gargle) with 5 ml of the solution. Time timed through an hourgla
Drug
Sponsors
Universidade de São Paulo
TRIALS - Oral Health
Eligibility
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Volunteer patients; age between 18 to 80 years; both genders; admitted to the State Hospital of Bauru / São Paulo; infected with SARS-CoV-2; infection in mild or moderate condition
Exclusion criteria
Exclusion criteria: Patients who are not able to perform daily mouthwash / gargle; refuse to participate in the research; those admitted to the ICU of the State Hospital of Bauru / São Paulo; do not present the age of the age group determined in the inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a reduction in the viral load of the experimental group in relation to the control, through the test of RT-PCR in salivary samples, considering that a reduction in the viral load is related to the clinical improvement of the patient | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find a more accelerated clinical improvement of patients in the experimental group compared to the control group, which will be verified using the Performance Status (PS) functional capacity scale. Still, with the collection of saliva at different times after the use of mouthwash, in both groups, it is expected to find a capacity for substantivity in the experimental group | — |
Countries
Brazil
Contacts
Public ContactBernardo;Paulo Sérgio Orcina;Santos
Universidade de São Paulo;Universidade de São Paulo
Outcome results
None listed