Skip to content

Effectiveness of water with ozone mouthrinse in plaque formation and gingival inflammation: a crossover randomized clinical trial

Effectiveness of ozonated water mouthrinse in early plaque formation and gingival inflammation: a crossover randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-57pgws
Enrollment
Unknown
Registered
2020-01-30
Start date
2019-08-20
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic gingivitis

Interventions

Test Group: 42 dental students, not brushing their upper theeth, will rinse 15 ml ozonated water daily for 4 days. After this period, they'll receive dental prophilaxys. Control Group: 42 dental stud
Other

Sponsors

Universidade Federal do Rio Grande do Sul
Lead Sponsor
Universidade Federal do Rio Grande do Sul
Collaborator

Eligibility

Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Informed consent signed; age between 18 and 40 years old; do not smoke; good systemic health; availability of 21 days to participate in the two experimental periods and the washout between them; 20 natural teeth, including the anterior teeth (excluding third molars); do not have restorations on the incisors, canines and premolars; do not use fixed or mobile orthodontic appliances; do not present anatomical irregularities such as enamel cracks; do not present gingival recession; do not present gingivitis and/or periodontitis; not having used antibiotics or anti-inflammatories within 30 days prior to the beginning of the trial period; do not present allergy to the product used; not being pregnant or breastfeeding; do not present tumors in the oral cavity.

Exclusion criteria

Exclusion criteria: Serious adverse events related to intervention

Design outcomes

Primary

MeasureTime frame
Asses the subgingival biofilm formation from the conversion of 0 and 1 to 2 using the method of Plaque Free Zone Index

Secondary

MeasureTime frame
Asses the crevicular gingival fluid volume using the method of measurement by Periotron;Asses the taste preference using the method of visual analogue scale;Asses the frequency of the adverse events

Countries

Brazil

Contacts

Public ContactAlessandra Cardoso Nicolini

Universidade Federal do Rio Grande do Sul

alessandrac_nicolini@hotmail.com+5551992868538

Outcome results

None listed

Source: REBEC (via WHO ICTRP)