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Influence of a respiratory physiotherapy technique on the blood flow in the brain of premature newborns

Influence of the selective insufflation respiratory physiotherapy technique on the cerebral hemodynamics of premature newborns

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-56swpv
Enrollment
Unknown
Registered
2020-10-02
Start date
2019-01-12
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

premature newbor

Interventions

This is an uncontrolled clinical trial. The intervention consists of an assessment of the cerebral hemodynamics of premature newborns through Doppler ultrasound before and after the application of a
final diastolic flow rate (VFFD)
resistance index (IR = VFPS-VFFD / VFPS). The evaluation will be made of at least five sequential stable waveforms for analysis. Using the Sono Site device, model M-Turbo®, with a 5 MHz transducer. Th
Other
E01.370.350.850.850
M01.060.703.520.520
E02.779

Sponsors

Universidade Federal do Paraná
Lead Sponsor
Universidade Federal do Paraná
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Newborn with gestational age between 25 and 34 weeks, admitted to the Neonatal Intensive Care Unit of the Clinical Hospital Complex. Term of consent signed by those responsible.

Exclusion criteria

Exclusion criteria: Premature with malformation of the central nervous system, chest and heart disease. Premature who present grade three or four hemorrhage on the first brain ultrasound examination prior to the intervention. Premature without indication of respiratory physiotherapy such as: before 72 hours of life, presence of pulmonary hemorrhage, severe pulmonary hypertension, non-drained pneumothorax, thrombocytopenia, omphalocele or uncorrected gastroschisis. Premature with contraindications to the use of the technique under study as: chest drainage, immediate postoperative of abdominal or thoracic surgeries.

Design outcomes

Primary

MeasureTime frame
It is expected that there will be no significant change in the brain resistance index assessed by cranial ultrasound with Doppler before and after the application of the respiratory physiotherapy technique.—

Secondary

MeasureTime frame
It is expected that there will be no variation in vital parameters: heart rate, respiratory rate, peripheral oxygen saturation and pain. Evaluator using a multiparametric monitor and pain using the NIPS scale.—

Countries

Brazil

Contacts

Public ContactÉvellin;Evellin Gomes;Gomes

Complexo Hospital de Clínicas;Complexo Hospital de Clínicas

evellinfisio@hotmail.com;evellinfisio@hotmail.com55 (41)33601825;+55-4133601825

Outcome results

None listed

Source: REBEC (via WHO ICTRP)