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Effect of Led Therapy (630 ± 20nm) in Herpes Simplex Labial

Effect of Led Therapy (630 ± 20nm) in Herpes Simplex Labial- Randomized Double-Blind Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-56f4w8
Enrollment
Unknown
Registered
2020-02-20
Start date
2017-09-11
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herpes simplex

Interventions

Control Group (CG): Four volunteers participated, received no therapy, only the simulation of LED therapy (equipment off). Aciclovir Group (GA): Four volunteers participated, taking aciclovir drug th
Drug
Radiation
Behavioural
D03.633.100.759.758.399.454.250
E02.594.540

Sponsors

Universidade do Vale do Paraiba UNIVAP
Lead Sponsor
Universidade do Vale do Paraiba UNIVAP
Collaborator

Eligibility

Age
18 Years to 59 Years

Inclusion criteria

Inclusion criteria: age between 18 and 59 years old, Caucasian, first manifestation of the disease, history of cold sores and / or presented the lesion, healthy individual without comorbidities, agree and sign the Informed Consent Form, after clarifying the research.

Exclusion criteria

Exclusion criteria: presence of neoplastic lesions in the oral environment; HSV-2 lesion in the genitalia; belonging to the Fitzpatrick V and VI classification scale; pregnant or lactating women; hypersensitivity to any component in the acyclovir formula; liver or kidney problems against acyclovir indication ; intraoral herpes; For ethical reasons excluded volunteers received conventional treatment guidance.

Design outcomes

Primary

MeasureTime frame
Primary outcome 1: Reduce disease onset time, number of recurrences, size of lesions, in the control period of five months after treatment. Checking by means of the patient's evaluation method with visual analog scale EVA, signs and symptoms lesion evaluation form and photographic control. From the observation of a variation of at least 5% in the pre and post-intervention measurements.;Expected outcome 1: Groups treated with low-level laser therapy have a higher performance compared to groups treated with conventional medication and control.—

Secondary

MeasureTime frame
Outcome found 1: Groups treated with conventional medication and control, presented slower repair times, recurrences in the control period, lesion size without decrease when recurrent. Groups treated with low-level laser therapy showed faster repair time and did not experience recurrences in the control period, five months.—

Countries

Brazil

Contacts

Public ContactMarcela Martins

Universidade do Vale do Paraiba UNIVAP

dramarcelalopes@icloud.com5512997519046

Outcome results

None listed

Source: REBEC (via WHO ICTRP)