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Evaluation of the effect of a 6% potassium nitrate gel on tooth sensitivity during and after office whitening in adult patients

Effectiveness of a 6% potassium nitrate gel on sensitivity during and after office bleaching in adults

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-567trz
Enrollment
Unknown
Registered
2019-10-16
Start date
2017-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin Sensitivity

Interventions

It will be a mouth-split study to assess the tooth sensitivity of 31 patients after office bleaching using hydrogen peroxide (HP) with and without the prior application of a 6% potassium nitrate (PN)
Bioexata Handling Pharmacy, Manaus, Brazil) (Figure 10) was applied to the other hemiarch following the same protocol. After removal of the gels, the gingival tissues of the teeth to be whitened from
Procedure/surgery
E06.420.750

Sponsors

Universidade Federal do Amazonas
Lead Sponsor
Universidade Federal do Amazonas
Collaborator

Eligibility

Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients of both sexes were included in the present study; aged between 18 and 40 years; who had at least six upper anterior teeth free of caries and restorations on the buccal surface; central or canine incisor with A2 or darker coloration; satisfactory oral hygiene; absence of periodontal disease.

Exclusion criteria

Exclusion criteria: The individuals excluded from the study were users of fixed orthodontic appliances; pregnant women; lactating women; severe intrinsic stains on teeth (stains due to tetracycline, fluorosis and pulped teeth); who were consuming any anti-inflammatory and antioxidant drugs; using desensitizing toothpaste; participants with a previous history of tooth sensitivity or any associated pathology (bruxism, gingival recession, noncarious lesion with dentin exposure).

Design outcomes

Primary

MeasureTime frame
Number of patients that report spontaneous pain in any moment of the bleaching protocol and up to 48 h post-bleaching, through self-report. This number will be presented as percentage of patients with tooth sensitivity and will be named absolute risk of tooth sensitivity.;The intensity of tooth sensitivity will be assessed using the visual analogue scale (VAS 0-10) and will be presented as means and standard deviations in different periods (during dental bleaching, up to 1 h, 1 h to 24 h and 24 h to 48 h post-bleaching).

Secondary

MeasureTime frame
The difference in color between the baseline condition and post-bleaching (1 week and 1 month) will be assessed by Vita Classical and Bleachedguide Vita shade guide as well as with the Vita Easyshade spectrophotometer. The data will be presented as means and standard deviations.

Countries

Brazil

Contacts

Public ContactPaulo Victor Martinho

Universidade Federal do Amazonas

drpvmartinho@gmail.com+5592981263100

Outcome results

None listed

Source: REBEC (via WHO ICTRP)