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Chronic effects of motor rehabilitation in Stroke survivors through Resistance Training and Neuromodulation

Motor rehabilitation in Stroke survivors with severe functional impairments through Unilateral Eccentric Training combined with Cortical Neuromodulation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-563rqd9
Enrollment
Unknown
Registered
2025-04-03
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke, not specified as haemorrhage or infarctio

Interventions

This study will be a double-blind randomized clinical controlled trial with a parallel intervention assignment. Twenty-eight patients (males and females), who have more than 18 years of age and had a
E02.760.169.063.500.387.875
E02.331.750
L01.224.160.875

Sponsors

Instituto de Física Gleb Wataghin
Lead Sponsor
Instituto de Física Gleb Wataghin
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who suffered a stroke (type 1) more than 6 months prior to participation in the study; patients who have severe hemeparesis as a consequence of the stroke; both female and male patients; patients above 18 years old

Exclusion criteria

Exclusion criteria: Patients who have any type of metal inside their body (pins, pacemakers, metal prostheses, revolver bullets); patients who have any musculoskeletal injury on the affected or unaffected limbs; patients who had previous conditions such as seizures, head trauma, hearing problems, and cochlear implants

Design outcomes

Primary

MeasureTime frame
We expect to find differences between groups, in which training from group 2 will lead to greater improvements in strength, power, muscle activity and active range of motion of the paretic limbs compared to group 1;We expect to find differences between groups, in which training from group 2 will lead to greater improvements in cortical connectivity and corticospinal excitability, and reductions in pre-synaptic and intracortical inhibition, which will facilitate the neural pathway for greater motor gains of the paretic limbs to occur compared to group 1;We expect to find differences between groups, in which training from group 2 will lead to greater improvements on muscle quality, cross-sectional area, thickness, pennation angle and fascicle length of the paretic muscles compared to group 1

Secondary

MeasureTime frame
We expect to find differences between groups, in which training from group 2 will lead to greater improvements on the same variables measured on the non-paretic limbs, and on the clinical and funcional performance tests compared to group 1

Countries

Australia, Brazil

Contacts

Public ContactCássio Víctora Ruas

Universidade Estadual de Campinas

c.victoraruas@ecu.edu.au+55(51)999087088

Outcome results

None listed

Source: REBEC (via WHO ICTRP)