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Study of the potentiation of propofol sedation by dipyrone

The role of Dipyrone as an adjuvant in the Sedation of adult patients with Propofol: Randomized, double blind and crossover clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-55z5hzf
Enrollment
Unknown
Registered
2024-09-18
Start date
2024-10-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Conscious Sedation

Interventions

In a randomized, double-blind, cross-trial clinical study, 12 volunteers will undergo conscious sedation with propofol (evaluated using bispectral index and AAO/S sedation scale). Before sedation, vol
E03.155

Sponsors

Associação Evangélica Beneficente de Londrina - AEBEL
Lead Sponsor
Anestesioclinica de Londrina
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Both sexes; 18-60 years old; American Society of Anesthesiologists (ASA) I and II functional classification

Exclusion criteria

Exclusion criteria: Personal history of allergic or pseudoallergic reactions to dipyrone; propofol and/or lidocaine; pregnant women; regular use of benzodiazepine medications; current history of chemical dependency; children; elderly (>60 years); ASA functional classification > II

Design outcomes

Primary

MeasureTime frame
Time intervals and propofol target required for each volunteer to reach the target of at least 75 on the BIS and OAA/S score of 3 in the absence and presence of a recent infusion of dipyrone—

Secondary

MeasureTime frame
Adverses effects—

Countries

Brazil

Contacts

Public ContactPaulo Herrera

Anestesioclinica de Londrina

clinicador@gmail.com+55 (43) 999957840

Outcome results

None listed

Source: REBEC (via WHO ICTRP)