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Evaluation of Magnesium Sulfate in Pain Relief in burn victims

Evaluation of the Analgesic Effect of Magnesium Sulfate in burn patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-55wtdr8
Enrollment
Unknown
Registered
2022-10-25
Start date
2022-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burns

Interventions

This is a randomized, controlled, two-arm, double-blind clinical trial. Experimental group: 57 burn victims participants will receive 40 mg/kg of intravenous magnesium sulfate diluted in 0.9% sodium c

Sponsors

Fundação de Ensino e Pesquisa em Ciências da Saúde/ FEPECS/ SES/ DF
Lead Sponsor
Hospital Regional da Asa Norte
Collaborator

Eligibility

Age
18 Years to 59 Years

Inclusion criteria

Inclusion criteria: Patients admitted to the burn treatment unit who will undergo balneotherapy and dressing change; of both genders; age between 18 and 59 years; classified in physical states I and II (according to the classification of the American Society of Anesthesiology); with 10 -20% burned body surface area; with more than 24 hours and less than 72 hours of hospitalization

Exclusion criteria

Exclusion criteria: Readmitted patients; outpatient balneotherapy/dressing; illicit drug users; previous pain syndromes; cognitive impairment; allergic to any component of the study; psychiatric disorders; pharmacodermia; myasthenia gravis; heart disease; hypermagnesemia; pregnant women; lactating women and creatinine elevation (>1.2 mg/dl)

Design outcomes

Primary

MeasureTime frame
Obtain the average pain scores using the numerical verbal scale (0-10) before Magnesium Sulfate infusion, after balneotherapy, after dressing change, 30 and 60 minutes of stay in the recovery room and compare it between the experimental and control group. ;Obtain the average of total morphine consumption and compare it between the experimental and control groups.

Secondary

MeasureTime frame
Describe side effects related to Magnesium Sulfate infusion, as well as its frequency.

Countries

Brazil

Contacts

Public ContactJoadyson Barbosa

Hospital Regional da Asa Norte

joadysonsb@hotmail.com+55 61 3325-4251

Outcome results

None listed

Source: REBEC (via WHO ICTRP)