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Treatment of dental Caries using laser

Influence of antimicrobial photodynamic therapy on carious lesion. Clinical analysis of the restorations and microbiological analysis of dentin

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-55jwmp
Enrollment
Unknown
Registered
2018-03-06
Start date
2017-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caries

Interventions

The clinical study is a split-mouth study. We will analyze the influence of low-intensity InGaAIP laser with 660 nm wavelength, red light spectrum region, 100mW power, 640 J / cm2 energy density, for
Other
E02.594

Sponsors

Universidade de São Paulo
Lead Sponsor
Universidade de São Paulo
Collaborator

Eligibility

Age
6 Years to 9 Years

Inclusion criteria

Inclusion criteria: The children analyzed in the study should be aged between 6 and 9 years of both genders and should have at least one lesion of active class I caries in homologous molars. It is necessary that this lesion reaches the dentin being deep or medium. The lesion should cover only the occlusal surface (Class I) considering that the pulp is vital and there is no sealant; amalgam or composite resin restorations in the study tooth.

Exclusion criteria

Exclusion criteria: Children who have teeth changes such as pain; spontaneous sensitivity; fistula; edema; mobility not compatible with stage of rhizolysis and present in the radiographic examination the presence of radiolucency in the region of furca and periápice; increased periodontal space and internal / external dental resorption will not be selected for the study.

Design outcomes

Primary

MeasureTime frame
During the course of this clinical study, we hope that the results promote reduction of microorganisms after the application of antimicrobial photodynamic therapy. This will be analyzed through a careful microbiological analysis of the dentin collected at three different moments for the teeth that will be submitted to the photodynamic therapy: before the selective removal, after the selective removal and after the application of antimicrobial photodynamic therapy, while for the teeth that will not receive the application of antimicrobial photodynamic therapy, this collection of dentin will be performed in two periods only: before the selective removal and after the selective removal. The collected dentin will undergo a serial dilution process and will be inoculated in plates with SB20 culture medium for the growth of Streptococcus mutans. Plates will be incubated in 10% CO2 at 37 ° C for 48 hours. The colony forming units (CFUs) will be counted, and the results will be expressed in CFU / mg remaining dentin.

Secondary

MeasureTime frame
Secondary outcomes are not expected.

Countries

Brazil

Contacts

Public ContactLuisa Gotardo Lara Alves

Faculdade de Odontologia de Ribeirão Preto

luisavalente_@hotmail.com+5501636233276

Outcome results

None listed

Source: REBEC (via WHO ICTRP)