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B12 Effect of supplementation and pulmonary rehabilitation in aerobic performance in patients with chronic obstructive pulmonary disease: a randomized study

Eight-week effect of physical training with vitamin B12 supplementation on functional capacity in patients with Chronic Obstructive Pulmonary Disease (COPD )

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-55f97c
Enrollment
Unknown
Registered
2015-07-14
Start date
2014-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

Intervention Rehabilitation Supplemented group: 8 participants who took part in pulmonary rehabilitation (aerobic exercise on a cycle ergometer and motor and respiratory exercise lasting about 40 minu
Dietary supplement
Other
Q65.060
G11.427.590.530.698.277

Sponsors

Universidade Federal de Mato Grosso do Sul - UFMS
Lead Sponsor
Universidade Federal de Mato Grosso do Sul - UFMS
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Volunteers with chronic obstructive pulmonary disease stages III and IV of the GOLD second disease; both sexes ; aged between 40 and 80 years ; at least four weeks free of disease exacerbation ; former smokers ; Current diagnosis or without other cardiopulmonary conditions such as asthma , interstitial lung disease , pulmonary hypertension , cardiac insufficiency or arthropathy , which does not allow exercise tests .

Exclusion criteria

Exclusion criteria: Volunteers with Chronic Obstructive Pulmonary Disease stages I and II of the disease according to GOLD criteria; participating in any program cardiopulmonary rehabilitation ; which show no ability to perform pulmonary function tests, gradual or exhaustive effort load constant; Volunteers with heart disease, dilated bronchi , rheumatic diseases , physical deformities that prevent the achievement of exercise or that are not available to participate.

Design outcomes

Primary

MeasureTime frame
It is expected from the improvement of functional capacity in patients with COPD, after eight weeks of periodized physical activity and vitamin B12 supplementation. For this purpose, will be examined through blood sample dosage of Vitamin B12 and through cardiopulmonary exercise testing constant load exercise time and the kinetic analysis during exercise. The variables are presented as mean and standard deviation and also confidence interval of 95%. In all cases a significance level of 5% will be adopted.

Secondary

MeasureTime frame
Once the physical capacity is considered an important marker in the development of COPD, multidimensional assessment, associating pulmonary variables and functional capacity, enables safe and effective interventions as well as more targeted pulmonary rehabilitation for this population, in addition to obtaining data that future may be taken into account in clinical variations important post-intervention measurements, when one takes into account many factors that affect exercise capacity.

Countries

Brazil

Contacts

Public ContactFernanda Paulin

Hospital Universitário Maria Aparecida Pedrossian

didivipa@hotmail.com+556733453149

Outcome results

None listed

Source: REBEC (via WHO ICTRP)