chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Volunteers with chronic obstructive pulmonary disease stages III and IV of the GOLD second disease; both sexes ; aged between 40 and 80 years ; at least four weeks free of disease exacerbation ; former smokers ; Current diagnosis or without other cardiopulmonary conditions such as asthma , interstitial lung disease , pulmonary hypertension , cardiac insufficiency or arthropathy , which does not allow exercise tests .
Exclusion criteria
Exclusion criteria: Volunteers with Chronic Obstructive Pulmonary Disease stages I and II of the disease according to GOLD criteria; participating in any program cardiopulmonary rehabilitation ; which show no ability to perform pulmonary function tests, gradual or exhaustive effort load constant; Volunteers with heart disease, dilated bronchi , rheumatic diseases , physical deformities that prevent the achievement of exercise or that are not available to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected from the improvement of functional capacity in patients with COPD, after eight weeks of periodized physical activity and vitamin B12 supplementation. For this purpose, will be examined through blood sample dosage of Vitamin B12 and through cardiopulmonary exercise testing constant load exercise time and the kinetic analysis during exercise. The variables are presented as mean and standard deviation and also confidence interval of 95%. In all cases a significance level of 5% will be adopted. | — |
Secondary
| Measure | Time frame |
|---|---|
| Once the physical capacity is considered an important marker in the development of COPD, multidimensional assessment, associating pulmonary variables and functional capacity, enables safe and effective interventions as well as more targeted pulmonary rehabilitation for this population, in addition to obtaining data that future may be taken into account in clinical variations important post-intervention measurements, when one takes into account many factors that affect exercise capacity. | — |
Countries
Brazil
Contacts
Hospital Universitário Maria Aparecida Pedrossian