breast cancer
Conditions
Interventions
Group A: Twenty female patients (20) submitted to mastectomies received pregabalin capsule 150 mg orally the night before surgery and continued for 14 days after 12 /12 hours.
Group B: Twenty-five fem
Drug
E01.370.600.550.324
Sponsors
Universidade Federal de Santa Maria
Universidade Federal de Santa Maria
Eligibility
Sex/Gender
Female
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Women's volunteers; scheduled for mastectomies; between 20 and 65 years; ASA II and III; without renal and hepatic comorbidities.
Exclusion criteria
Exclusion criteria: Women's Volunteers; scheduled for mastectomies; with hepatic and / or renal comorbidities; with BMI greater than 40; with low cognitive degree; not agreeing to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of chronic postoperative pain in mastectomies with the perioperative use of pregabalin, verified by the Mann-Whitney test, based on a variation of at least 5%.;There was no reduction of postoperative chronic pain in patients who used pregabalin, both verified by Mann-Whitney test, based on a variation of at least 5%. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of acute postoperative pain in mastectomies after the use of perioperative pregabalin verified by the Mann-Whitney test, based on a variation of at least 5%.;There was a reduction in postoperative acute pain evaluated by the lower consumption of morphine in the first 24 hours postoperatively, based on a variation of at least 5%. | — |
Countries
Brazil
Contacts
Public ContactMiriam Menezes
Universidade Federal de Santa Maria
Outcome results
None listed