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Efficacy of tylex-associated to a desensitizer in tooth sensitivity induced by office bleaching

Efficacy of codeine/paracetamol-associated to a desensitizer in tooth sensitivity induced by office bleaching: a randomized, controlled, triple-blind clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
REBEC
Registry ID
RBR-54xy8b
Enrollment
Unknown
Registered
2019-10-01
Start date
2019-04-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin Sensitivity

Interventions

n total = 80 G1 - placebo group (2 subgroups) n = 40 Participants should receive the placebo capsules that are given 1 hour before the procedure and every 6 hours for 48 hours. • G1A: hemiarked (elem
Drug
Other

Sponsors

Universidade Federal do Rio Grande do Norte
Lead Sponsor
Universidade Federal do Rio Grande do Norte
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients should be at least 18 years of age; good general and oral health; upper anterior teeth with no restorations; never bleached before.

Exclusion criteria

Exclusion criteria: Patients who present previous restorations; pregnant or breastfeeding; have discoloration of the dental element caused by trauma; severe fluorosis; darkening caused by endodontic treatment and requiring internal bleaching (non-vital); habits of bruxism or without good oral health; any previous or current health problems (in the stomach, heart, kidney and liver); continuous use of anti-inflammatory drugs and/or analgesics; systemic diseases such as diabetes, hypertension; known allergy to codeine phosphate 30mg/paracetamol 500mg.

Design outcomes

Primary

MeasureTime frame
Codeine phosphate 30mg/paracetamol 500mg administered 1 hour prior to tooth bleaching and every 6 hours for 48 hours in combination with desensitizing agent may reduce the risk and/or intensity of dental sensitivity levels induced by office bleaching.

Secondary

MeasureTime frame
The coloration of the teeth will not be affected by the tested therapy of codeine phosphate 30mg/paracetamol 500mg in combination with the desensitizer, that is, the effectiveness of the whitening will be maintained.

Countries

Brazil

Contacts

Public ContactIsabela;Kaiza de Araújo;Santos

Universidade Federal do Rio Grande do Norte;Universidade Federal do Rio Grande do Norte

isabeladta@gmail.com;kaizasousasantos@gmail.com+55-084-988384090;+55-084-98955148

Outcome results

None listed

Source: REBEC (via WHO ICTRP)