Hypertension
Conditions
Interventions
Both groups will consist of 30 participants each and will perform the intervention three times a week for 12 weeks.
The intervention group will perform the high intensity interval training, which will
G11.427.410.698.277.311.250
Sponsors
Pontifícia Universidade Católica de Goiás
Pontifícia Universidade Católica de Goiás
Eligibility
Age
18 Years to 59 Years
Inclusion criteria
Inclusion criteria: Patients aged between 18 and 59 years; hypertensive without treatment or using up to three antihypertensive drugs will be included; stable dose of antihypertensive medication in the last month; not having exercised in the last 3 months; and who are in possession of medical clearance to perform high-intensity physical exercise.
Exclusion criteria
Exclusion criteria: Smokers; individuals with decompensated heart disease; hypertensive patients with blood pressure levels greater than 180x110 mmHg; chronic renal patients with a glomerular filtrate rate less than 30 ml; individuals with hyperthyroidism or confirmed hypothyroidism; cognitive dysfunction that disables the execution or understanding of the study procedures or intervention; lung disease that disables the exercise; patients using beta-blockers or antiarrhythmic drugs; cancer diagnosis; presence of an orthopedic or neurological condition that makes it difficult to perform the exercises.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure: it will be assessed by means of the Home Blood Pressure Monitoring (HBPM), which consists of the measurement of blood pressure by the patient himself or by a trained family member. The pressure assessment by HBPM will follow the following protocol: the patient will measure his pressure for five days, on the first day, two control measures will be taken in the office, which will later be discarded, and in the next four days, three measures will be taken in the period morning and three measurements at night. Blood pressure will be assessed before and after the intervention.;Pulse wave velocity: it will be evaluated by central blood pressure measurement, which will be made using the Mobil-O-Graph® device, by means of a non-invasive measurement, with a cuff that measures the peripheral parameters and estimates, using the ARCSolver algorithm, the value of blood pressure and pulse wave velocity (PWV) at the level of the aorta. PWV will be assessed before and after the intervention.;Aerobic fitness: will be verified through the Exercise Test that will be performed on a Centurion 200 electronic treadmill (Micromed, Brasília, Brazil) using the modified ramp-free protocol. Participants will stay for 3 minutes in pre-exercise rest in the orthostatic position, then a 2-minute warm-up will be performed at a speed of 5 km/h, with an increase of 1 km/h every 1 minute, followed by 6 minutes in active recovery with speed at 2 km/h. VO2peak will be estimated based on the duration of the test and according to gender. During the execution of the protocol, heart rate will also be collected, including the maximum heart rate reached, called peak heart rate, systolic and diastolic blood pressure and the subjective perception of effort, using the Borg Scale. Aerobic fitness will be assessed before and after the intervention.;Respiratory muscle strength: will be assessed with manovacuometry, using the maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP), u | — |
Secondary
| Measure | Time frame |
|---|---|
| Central systolic blood pressure: will be assessed using the central blood pressure measurement with Mobil-O-Graph®. This assessment is done in a non-invasive way, with a cuff that measures peripheral pressures and estimates the value of blood pressure at central level, level of the aorta. Central systolic and diastolic pressures will be assessed before and after the intervention.;Distance covered in the Exercise Test: it will be verified through the Exercise Test that will be performed on a Centurion 200 electronic treadmill (Micromed, Brasília, Brazil) using the modified ramp protocol without modification. Participants will stay for 3 minutes in pre-exercise rest in the orthostatic position, then a 2-minute warm-up will be performed at a speed of 5 km/h, with an increase of 1 km/h every 1 minute, followed by 6 minutes in active recovery with speed at 2 km/h. At the end, the distance covered by the patient during the entire test will be checked. The distance covered will be assessed before and after the intervention. | — |
Countries
Brazil
Contacts
Public ContactRayne Fagundes
Outcome results
None listed