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The influence of physical activity for patients with liver cirrhosis

Effect of physical exercise in cirrhotic patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-54ngrx
Enrollment
Unknown
Registered
2020-03-18
Start date
2015-03-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cirrhosis

Interventions

Experimental group: 19 patients of both sexes, with liver cirrhosis who underwent 12 weeks of physical exercise. The design and progression of the program was adapted from the positioning of physical
Behavioural
G11.427.410.698.277

Sponsors

Universidade Federal do Rio de Janeiro
Lead Sponsor
Hospital Universitário Clementino Fraga Filho
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years; Carrier of liver cirrhosis.

Exclusion criteria

Exclusion criteria: Smoking; coronary disease; presence of hepatocellular carcinoma; use of vasoactive drugs (except propranolol); use of current interferon or in the last 3 months; use of corticosteroids; duration of the infectious condition; upper gastrointestinal bleeding in the last two weeks; pregnant; musculoskeletal injuries; upper digestive endoscopy with medium or large caliber esophageal varices without eradication.

Design outcomes

Primary

MeasureTime frame
It is expected that the experimental group, submitted to the intervention with physical exercises, will show an improvement in the physical conditioning evaluated by the increase in muscle strength and cardiorespiratory capacity.;Our results confirm the expected primary outcome, by showing an improvement in handgrip strength, in the total training volume and the variables of cardiorespiratory capacity in the experimental group, in the post-intervention moment when compared to the pre-intervention. In the control group, we observed a worsening or a picture of stability concerning the same variables analyzed.

Secondary

MeasureTime frame
It is expected that with the improvement of the physical condition, the experimental group submitted to physical exercises will improve their perception of quality of life.;Our results confirm the expected secondary outcome, by showing an improvement in the domains of the SF-36 questionnaire on the perception of functional capacity, limitations due to physical aspects, pain, general health status and limitations due to social and emotional aspects, at the time when compared to the pre-intervention moment. In the control group, we did not observe differences concerning the moments of the study.

Countries

Brazil

Contacts

Public ContactAmanda Brown

Universidade Federal do Rio de Janeiro

afbrown.ufrj@gmail.com+55-32-991819213

Outcome results

None listed

Source: REBEC (via WHO ICTRP)