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Evaluation of Root Coverage by Connective Graft and Different Root Conditioning Adjunctive Therapies

Effects of Photobiomodulation and Antimicrobial Photodynamic Therapy Associated With Subepithelial Connective Tissue Graft on the Root Coverage of Multiple Gingival Recessions: A Randomized Controlled Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-54d3t3
Enrollment
Unknown
Registered
2019-10-20
Start date
2018-04-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Recession

Interventions

This study is a parallel design with three arms, the selecionated sites will be allocated in three diferent treatment groups: Contro group: conventional treatment by scaling and root planning (Gracey
Antimicrobial photodinamic therapy: treatment by scaling and root planning followed by antimicrobial photodinamic therapy (toluidine blue O by 1 minute 10mg/ml in a deionized water, pH 3-4 plus laser
Laser group: treatment by scaling and root planning and and root coverage by connective tissue graft, followed by laser THERAPY XT application by laser InAlGaP, 1J per point, red laser, 41J/cm², 14s,
Patients will be assisted by twelve months after the surgical procedure.
Procedure/surgery
E06.721

Sponsors

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Collaborator
Faculdade de Odontologia de Bauru-Universidade de São Paulo
Lead Sponsor
Faculdade de Odontologia de Bauru-Universidade de São Paulo
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: gingival recession in two or more adjacent teeth (multiple recession type defects); teeth witout root canal treatment; Patients without signals of periodontal disease and with plaque and gingival index in all mouth lesser than 20%; And patients that agree to the free and informed consent terms

Exclusion criteria

Exclusion criteria: Patients with systemic diseases that contraindicate surgical procedures or affect the course of healing; Patients who use medication that interferes with the healing process or who use anticonvulsant, antihypertensive or cyclosporine medications, or who have systemic diseases that pose a risk when performing surgical procedures; Smokers, pregnant women; Patients who have previously undergone periodontal surgery in the area of interest. And patients with orthodontic therapy in progression;

Design outcomes

Primary

MeasureTime frame
Primary outcome for sample calculation: expected as a clinical target of root coverage average of 80% for the three groups; ;Reduction in the size of the gingival recessions over a period of one year, measured with the aid of a periodontal probe in mm, by the distance from the gingival margin to the enamel cementum junction, from the finding of a variation of at least 5% in pre and post measurements intervention.—

Secondary

MeasureTime frame
Secondary outcomes are not expected;—

Countries

Brazil

Contacts

Public ContactFaculdade de Odontologia de Bauru FOB USP

Universidade de São Paulo, Faculdade de Odontologia de Bauru

fob@usp.br+55(14) 3235-8000

Outcome results

None listed

Source: REBEC (via WHO ICTRP)