Effects of Transcranial Stimulation and balance training in individuals with Parkinson: a randomized clinical trial

Effects of Transcranial Direct Current Stimulation (tDCS) associated with balance training in individuals with Parkinson's disease: randomized clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

REBEC

Registry ID

RBR-52y3zgd

Enrollment

Registered

2022-07-11

Start date

2022-08-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postural balance. Parkinson&apos

Interventions

Thirty-six individuals diagnosed with Parkinson&apos

s disease will be recruited and contacted by the principal researcher via telephone using contact information available in medical records and invited to participate in the study. If they agree to par

Eligibility

Inclusion criteria

Inclusion criteria: Individuals of both sexes; regardless of age; with a clinical diagnosis of Parkinson’s disease; classified as stage 3 or 4 on the Hoehn and Yahr scale; and who agreed to participate in the study by signing the Informed Consent Form

Exclusion criteria

Exclusion criteria: Individuals with neurological disorders other than Parkinson’s disease; cognitive deficits that prevented performance of assessments; scores lower than 8 on the 10 Point Cognitive Screener; those undergoing Physiotherapy at screening; those who had undergone Physiotherapy less than 1 month before enrollment; or those with a Deep Brain Stimulation device were excluded

Design outcomes

Primary

Measure	Time frame
Expected outcome 1: An improvement in postural control is expected, as assessed by the Mini Balance Evaluation Systems Test, considering an increase of 3.4 points in the total score as the minimum clinically significant difference. Both groups are expected to improve after the intervention; however, the Experimental Group, submitted to Postural Control Training associated with Transcranial Direct Current Stimulation, is expected to demonstrate greater improvement than the Placebo Group, submitted to Postural Control Training associated with placebo Transcranial Direct Current Stimulation;Observed outcome 1: An improvement in postural control was observed, as assessed by the Mini Balance Evaluation Systems Test, in both groups after the intervention. However, no statistically significant difference was observed between the Experimental Group, submitted to Postural Control Training associated with Transcranial Direct Current Stimulation, and the Placebo Group, submitted to Postural Control Training associated with placebo Transcranial Direct Current Stimulation, indicating no additional benefit of Transcranial Direct Current Stimulation	—

Measure

Time frame

Expected outcome 1: An improvement in postural control is expected, as assessed by the Mini Balance Evaluation Systems Test, considering an increase of 3.4 points in the total score as the minimum clinically significant difference. Both groups are expected to improve after the intervention; however, the Experimental Group, submitted to Postural Control Training associated with Transcranial Direct Current Stimulation, is expected to demonstrate greater improvement than the Placebo Group, submitted to Postural Control Training associated with placebo Transcranial Direct Current Stimulation;Observed outcome 1: An improvement in postural control was observed, as assessed by the Mini Balance Evaluation Systems Test, in both groups after the intervention. However, no statistically significant difference was observed between the Experimental Group, submitted to Postural Control Training associated with Transcranial Direct Current Stimulation, and the Placebo Group, submitted to Postural Control Training associated with placebo Transcranial Direct Current Stimulation, indicating no additional benefit of Transcranial Direct Current Stimulation

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Secondary

Measure	Time frame
Expected outcome 2: An improvement in gait is expected, as assessed by the 10-Meter Walk Test, considering an increase of 0.18 meters per second in gait speed as the minimum detectable change. Both groups are expected to improve after the intervention; however, the Experimental Group, submitted to Postural Control Training associated with Transcranial Direct Current Stimulation, is expected to demonstrate greater improvement than the Placebo Group, submitted to Postural Control Training associated with placebo Transcranial Direct Current Stimulation;Observed outcome 2: An improvement in gait was observed, as assessed by the 10-Meter Walk Test, in both groups after the intervention. However, no statistically significant difference was observed between the Experimental Group and the Placebo Group;Expected outcome 3: Evaluate functional mobility using the Timed Up and Go test, considering clinical improvement as a reduction in the time required to stand up from a chair, walk 3 meters, return, and sit down again. Both groups are expected to improve after the intervention; however, the Experimental Group, submitted to Postural Control Training associated with Transcranial Direct Current Stimulation, is expected to demonstrate greater improvement than the Placebo Group, submitted to Postural Control Training associated with placebo Transcranial Direct Current StimulationAn improvement in functional mobility is expected, as assessed by the Timed Up and Go test, considering a reduction in the time required to stand up from a chair, walk three meters, return, and sit down again as the parameter of improvement. Both groups are expected to improve after the intervention; however, the Experimental Group, submitted to Postural Control Training associated with Transcranial Direct Current Stimulation, is expected to demonstrate greater improvement than the Placebo Group, submitted to Postural Control Training associated with placebo Transcranial Direct Current Stimulation;Observed	—

Measure

Time frame

Expected outcome 2: An improvement in gait is expected, as assessed by the 10-Meter Walk Test, considering an increase of 0.18 meters per second in gait speed as the minimum detectable change. Both groups are expected to improve after the intervention; however, the Experimental Group, submitted to Postural Control Training associated with Transcranial Direct Current Stimulation, is expected to demonstrate greater improvement than the Placebo Group, submitted to Postural Control Training associated with placebo Transcranial Direct Current Stimulation;Observed outcome 2: An improvement in gait was observed, as assessed by the 10-Meter Walk Test, in both groups after the intervention. However, no statistically significant difference was observed between the Experimental Group and the Placebo Group;Expected outcome 3: Evaluate functional mobility using the Timed Up and Go test, considering clinical improvement as a reduction in the time required to stand up from a chair, walk 3 meters, return, and sit down again. Both groups are expected to improve after the intervention; however, the Experimental Group, submitted to Postural Control Training associated with Transcranial Direct Current Stimulation, is expected to demonstrate greater improvement than the Placebo Group, submitted to Postural Control Training associated with placebo Transcranial Direct Current StimulationAn improvement in functional mobility is expected, as assessed by the Timed Up and Go test, considering a reduction in the time required to stand up from a chair, walk three meters, return, and sit down again as the parameter of improvement. Both groups are expected to improve after the intervention; however, the Experimental Group, submitted to Postural Control Training associated with Transcranial Direct Current Stimulation, is expected to demonstrate greater improvement than the Placebo Group, submitted to Postural Control Training associated with placebo Transcranial Direct Current Stimulation;Observed

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Countries

Contacts

Public ContactRaynara dos Santos

Universidade Federal do Amazonas

raynara_fs@outlook.com+55(92)992834548

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Aug 9, 2026