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Effect of caffeine supplementation on physical performance and oxidative stress during high-intensity exercises

Effect of caffeine supplementation at physical performance and balance redox during a high-intensity interval training (HIIT) protocol

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-52twgg
Enrollment
Unknown
Registered
2020-04-22
Start date
2017-01-20
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caffeine

Interventions

Experimental group 1: 16 healthy recreational active men with no high caffeine consumption were selected to participate in the study, receiving an average dose of caffeine (6mg. Kg body). Experimental
Dietary supplement
G07.203.300.456

Sponsors

Universidade Federal do Paraná
Lead Sponsor
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Collaborator

Eligibility

Sex/Gender
Male
Age
18 Years to 23 Years

Inclusion criteria

Inclusion criteria: Recreationally active adults; practicing strength training at least 150 minutes a week; male

Exclusion criteria

Exclusion criteria: Habitual caffeine users; individuals not used to strength training; be participating in another study during the analyzes; present an injury or physical impairment that prevented the tests from being performed; cardiovascular diseases; smoker; use of other supplements during testing

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: Assess whether supplementation with high doses of caffeine (8mg. Kg body) promotes more significant improvements in maximum strength when compared to the control group (15-20% better) or lower doses of caffeine (5-8% better ), being evaluated through a protocol of 10 maximum repetitions (10-RM) in the bench press, squat and deadlift exercises to estimate the one maximum repetition values.;Outcome found 1: It was observed that supplementation with higher doses of caffeine (8mg. Kg body) promoted significant improvements in the estimation of the maximum strength, analyzed through the 10-RM test, improving the strength by 7.5% in the bench press, 10.6% in the squat and 12.9% in the deadlift compared to the control group, presenting less expressive results when compared to the lower doses of caffeine, raising the estimated maximum strength in the bench press by 3.4%, 5.2% in the squat and 8.5% on the deadlift.

Secondary

MeasureTime frame
Expected outcome 1: Assess whether supplementation with higher doses of caffeine promotes more significant reductions in the perceived exertion compared to the control group (reductions of 20-30%) and lower doses of caffeine (reductions of 5-10%), being assessed through the OMNI perception scale.;Outcome found 1: It was observed that there were no significant differences between the rate of perceived exertion observed through the OMNI scale between the group that supplemented with higher doses of caffeine with the control group (~3%). The group that supplemented with moderate doses of caffeine had a 15% higher rate of perceived exertion compared to the group that supplemented with a higher dose of caffeine and 17% higher when compared to the control group.;Expected outcome 2: Assess whether high doses of caffeine promote significant reductions in the global oxidative stress variables compared to the control group (reductions of 10-15%), as well as singular reductions (<5%) when compared to moderate caffeine doses. The analyzes of the global oxidative stress were made through blood collections, which sought to analyze the levels of lactate, lactate dehydrogenase, ferritin, and superoxide dismutase.;Outcome found 2: Higher doses of caffeine promoted significant reductions (14%) in global levels of oxidative stress (lactate, lactate dehydrogenase, ferritin, and superoxide dismutase) when compared to the control group. Reductions of ~5% were observed when comparing higher doses of caffeine with moderate doses.

Countries

Brazil

Contacts

Public ContactLuis Boiko Ferreira

Universidade Federal do Paraná

lhboikoferreira@gmail.com+55042998292175

Outcome results

None listed

Source: REBEC (via WHO ICTRP)