Dental caries
Conditions
Interventions
The study will be divided into two stages, with 60 participants in total. The first stage is a randomized, crossover, controlled, two-arm, double-blind, longitudinal clinical trial. 30 participants wi
Tenuta
Cury, 2014). On the day of the intervention, with at least two hours of fasting, volunteers will brush with 1 g of toothpaste (1 min), with coded packaging, followed by rinsing with 10 mL of distilled
Larsen et al., 2019 ). At least 2 mL of unstimulated saliva will be collected. This will be collected using a plastic device and stored in sterile microtubes (Eppendorfs®). After that, the samples wil
E06.761.726.794
Sponsors
Departamento de Farmácia - Universidade Federal do Ceará
Departamento de Farmácia - Universidade Federal do Ceará
Eligibility
Age
8 Years to 18 Years
Inclusion criteria
Inclusion criteria: Individuals with orthodontic braces; aged between 8 - 18 years;both genders; individuals with visible plaque; individuals with at least 20 teeth; individuals with no caries lesions
Exclusion criteria
Exclusion criteria: Pregnant women; allergy history; systemic diseases; use of professional fluorides in the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that Brazilian red propolis dentifrice has anti-caries effects, in the prevention of lesions and oral fluoride bioavailability similar or superior to the common fluoride dentifrice. | — |
Secondary
| Measure | Time frame |
|---|---|
| Brazilian red propolis dentifrice is expected to reduce bacterial plaque and present biomarkers with results similar to or better than the common fluoride dentifrice. | — |
Countries
Brazil
Contacts
Public ContactLidia Marques
Universidade Federal do Ceará
Outcome results
None listed