Hypercholesterolemia, Oxidative stress
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Men and women alduts (19 - 60 years old); omnivores; BMI between 18.5 and 30 kilogram per meter squared; total cholesterol between 50-95 th percentile (NCEP - National Cholesterol Education Program): between 200 and 255 mg/dL for men and between 201 and 265 mg/dL for women,
Exclusion criteria
Exclusion criteria: Use of any nutritional intervention and/or drugs, such omega 3 or dietary fiber; vegetarians; presence of chronic diseases, such hypertension, diabetes, cardiovascular disease or cancer; chronic alcoholics (consumption more than 2 times a week); frequent consumption of nuts (more than 2 times a week); allergy of nuts.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 10% of reduction in serum LDL-c, after 6 weeks of supplementation with baru almond.;Serum LDL-c reduced 9.4% after 6 weeks of supplementation with baru almond. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of cholesterol total, triglycerides and homocysteine concentrations. Increase of plasma total antioxidant capacity and improve of oxidative status. Maintenance of the body composition and dietary intake. ;There was a significant reduction of 8.1% in total cholesterol and non-significant 10.4% for triglycerides. The homocysteine??, total antioxidant capacity, oxidative status, body composition and dietary intake did not changed during the study. | — |
Countries
Brazil
Contacts
Faculdade de Nutrição da Universidade Federal de Goiás;Faculdade de Nutrição da Universidade Federal de Goiás