Parkinson Disease
Conditions
Interventions
It is a single-blind randomized controlled clinical trial. 40 participants with Parkinson's disease will be randomly allocated into 2 groups: i) aerobic training and ii) control. In both groups, inte
G11.427.410.698.277
Sponsors
Universidade Nove de Julho
Associação Brasil Parkinson
Eligibility
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Individuals of both sexes having a previous diagnosis of Parkinson's disease; be undergoing pharmacological treatment for PD; be at least 40 years old
Exclusion criteria
Exclusion criteria: Being in Hoehn & Yahr stages 4 and 5 of Parkinson's disease; have other neurological diseases in addition to Parkinson's disease; present a previous diagnosis of cardiovascular disease (except systemic arterial hypertension) or presence of symptoms suggestive of an unknown cardiovascular disease; inability to move independently without the aid of aids; present contraindications for aerobic training; be performing aerobic training regularly; have long COVID; severe cognitive impairment defined by a score lower than 18 on the Mini Mental State Examination
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a greater improvement in global cognition, verified by the Montreal Cognitive Assessment (MoCA) after aerobic training in comparison to the control group, based on the finding of a statistically significant interaction between the factors group and time defined as a value of P < 0.05.;It is expected to find an improvement in the non-motor symptoms of Parkinson's disease, verified by the Non-Motor Symptom Assessment Scale in Parkinson's Disease (NMSS) after aerobic training in comparison to the control group, based on the finding of a statistically significant interaction between the factors group and time defined as a value of P < 0.05. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find an improvement in sleep quality, assessed by the Parkinson's Disease Sleep Scale (PDSS) after aerobic training in comparison to the control group, based on the finding of a statistically significant interaction between the factors group and time defined as a P value < 0.05.;It is expected to find an improvement in anxiety symptoms, assessed by the Parkinson Anxiety Scale (PAS) after aerobic training in comparison to the control group, based on the finding of a statistically significant interaction between the factors group and time defined as a P value < 0.05.;It is expected to find an improvement in depression symptoms, assessed by the Geriatric Depression Scale (GDS) after aerobic training in comparison to the control group, based on the finding of a statistically significant interaction between the factors group and time defined as a value of P < 0.05.;It is expected to find an improvement in apathy levels, assessed by the Apathy Inventory after aerobic training in comparison to the control group, based on the finding of a statistically significant interaction between the factors group and time defined as a value of P < 0, 05.;It is expected to find an improvement in fatigue levels, assessed by the Parkinson Fatigue Scale (PFS) after aerobic training in comparison to the control group, based on the finding of a statistically significant interaction between the factors group and time defined as a value of P < 0.05.;It is expected to find an improvement in pain intensity, assessed by the Numerical Rating Scale (NRS) after aerobic training in comparison to the control group, based on the finding of a statistically significant interaction between the factors group and time defined as a value of P < 0.05.;It is expected to find an improvement in quality of life, assessed by the Parkinson's Disease Questionnaire (PDQ-8) after aerobic training in comparison to the control group, based on the finding of a statistically significant interaction betwe | — |
Countries
Brazil
Contacts
Public ContactRafael Fecchio
Universidade Nove de Julho
Outcome results
None listed