Platelet-Rich Fibrin
Conditions
Interventions
This is a randomized, controlled, double-blind clinical study in which blood samples were collected from 20 volunteers. The blood samples were donated by patients undergoing routine medical blood coll
each was assigned a number corresponding to their laboratory specimen for subsequent analysis
Sponsors
Faculdade São Leopoldo Mandic
Faculdade São Leopoldo Mandic
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: For the control group, healthy volunteers will be selected; classified as ASA 1 by the American Society of Anesthesiologists; of both genders; non-smokers; aged between 18 and 85 years; and with no recent history of using any type of medication. For the experimental group, cardiac patients who are regularly using anticoagulants will be selected
Exclusion criteria
Exclusion criteria: Patients with more than one disease; drug users; or who do not fit into the groups described above will be excluded from the research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: It is expected to find discrepancies in the quality of autologous fibrin membranes in cardiac patients using platelet anticoagulants, focusing on macroscopic and microscopic characteristics and growth factor levels, when compared to healthy patients;Outcome found 1: It was observed, from the results obtained, indicating that anticoagulants may interfere in the formation of the fibrin mesh and consequently in its quality and regenerative capacity | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes were expected | — |
Countries
Brazil
Contacts
Public ContactVilton de Souza
Faculdade São Leopoldo Mandic
Outcome results
None listed