Skip to content

Effect of hydroxyapatite paste on human enamel

In vitro and in situ effects of nano hydroxyapatite in bleached enamel with hydrogen peroxide

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4ymcyc
Enrollment
Unknown
Registered
2015-09-16
Start date
2013-01-03
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Demineralization

Interventions

GC (negative control group) - 1 individual was securing 5 specimens on the labial surface of the upper and lower molars. This group was not performed bleaching treatment. Subjects were evaluated every
GnHAP (experimental group 2) - 1 individual was securing 5 specimens treated with nanohidroxiapatita folder prior to bleaching with 35% hydrogen peroxide. Subjects were evaluated every seven days for
Other

Sponsors

Universidade Federal do Pará
Lead Sponsor
Universidade Federal do Pará
Collaborator

Eligibility

Age
20 Years to 22 Years

Inclusion criteria

Inclusion criteria: 3 persons aged between 20 and 22 years; Height of the clinical crown of the upper molars above 5 mm; absence of cavities; absence of periodontal disease; normal oral pH around 7.0; normal salivary flow.

Exclusion criteria

Exclusion criteria: Patients with dentin sensitivity; gastroesophageal disturbances; pregnant or nursing women; patients with fixed prostheses or removable orthodontic appliances; drug users or smokers; and practitioners of water sports.

Design outcomes

Primary

MeasureTime frame
Absence of significant difference between the mean microhardness only in Control Group and Experimental Group 2 (GnHAP), verified by the Knoop microhardness test, obtained at baseline and after three weeks of study. No interference in the results bleaching treatment in experimental groups verified by colorimetry triistimulus from the finding of the increase in the value of Delta E (indicating the success of bleaching treatment), after 3 weeks of evaluation.;There was no significant difference between the mean microhardness in Control Group and Experimental Group 2 (GnHAP), verified by the Knoop microhardness test, obtained at baseline and after three weeks of study. There was a significant decrease in Knoop microhardness of the specimens GHP (experimental group 1) after 3 weeks of study compared to the initial reading. There was no interference in the results bleaching treatment in experimental groups verified by colorimetry triistimulus from the finding of the increase in the value of Delta E (indicating the success of bleaching treatment), after 3 weeks of evaluation, in all experimental groups.

Secondary

MeasureTime frame
It is expected observe a morphology similar between the GC (control group) and GnHAP (experiment 2) and different pattern observed in the GHP (group Experimental 1) by means of microscopy Scanning electron after 3 weeks evaluation.;There was a similar morphological pattern among all groups studied, verified by scanning electron microscopy after 3 weeks of evaluation.

Countries

Brazil

Contacts

Public ContactCecy Silva

Universidade Federal do Pará

cecymsilva@gmail.com+559132017637

Outcome results

None listed

Source: REBEC (via WHO ICTRP)