FindTrial
Sign In

Preemptive use of drugs improves Endodontic Treatment of symptomatic teeth

Effect of preemptive use of a Nonsteroidal Anti-Inflammatory drug and a Corticosteroid on the efficacy of inferior alveolar nerve blockade and postoperative Pain control in Endodontic Treatment of molars with Symptomatic Pulpitis: a randomized double-blind placebo-controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4y22q9z
Enrollment
Unknown
Registered
2023-05-18
Start date
2021-09-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulpitis

Interventions

This is a three-arm, double-blind, randomized controlled clinical trial. Control group: 28 patients will receive endodontic treatment and will receive the administration (orally) of a pill of a placeb
E06.397
D27.505.696.663.850.014.040.500

Sponsors

Centro de Pesquisas Odontológicas São Leopoldo Mandic SS
Lead Sponsor
Centro de Pesquisas Odontológicas São Leopoldo Mandic SS
Collaborator

Eligibility

Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Healthy patient (American Association of Anesthesiologists - class I); having lower molar diagnosed with irreversible symptomatic pulpitis; aged between 20 and 45 years; both genders; endodontic treatment performed within the interval between 80 and 90 minutes performed in patients who did not take any type of analgesic medication in the 12 hours preceding the endodontic treatment

Exclusion criteria

Exclusion criteria: Patients allergic or intolerant to diclofenacs, dexamethasone, articaine or any other drug/material used in this study; pregnant or lactating women; teeth with periodontal problems or radiographic images suggestive of internal/external resorptions; endodontic treatments not completed in a single session

Design outcomes

Primary

MeasureTime frame
To evaluate the effect of using preemptive oral medication with dexamethasone or diclofenac potassium on the success of inferior alveolar nerve block 15 minutes after anesthesia and its influence on postoperative pain intensity 6, 12, 24, 48 and 72 hours after the end of the endodontic procedure.—

Secondary

MeasureTime frame
Secondary outcomes are not expected.—

Countries

Brazil

Contacts

Public ContactJuliana Bronzato

Centro de Pesquisas Odontológicas São Leopoldo Mandic SS

julianadelatorre_@hotmail.com+55(19)996994390

Outcome results

None listed

Source: REBEC (via WHO ICTRP)