Chronic kidney disease
Conditions
Interventions
Patients with hemodialysis chronic kidney disease from the Department of Nephrology at the Hospital de Clínicas de Porto Alegre (HCPA) and the Instituto de Doenças Renais (IDR) will be randomized into
Device
Behavioural
Other
G11.427.590.530.698.277
E01.370.600.425
Sponsors
Universidade Federal do Rio Grande do Sul - UFRGS
Hospital de Clínicas de Porto Alegre - HCPA / UFRGS
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Diagnosis of Chronic Kidney Disease more than six months. Patients in hemodialysis for at least 3 months. Patients in hemodialysis at the Nephrology Department of the Hospital de Clinicas de Porto Alegre or in the Instituto de Doenças Renais Older than 18 years. Sedentary. Physical condition to perform exercises and tests proposed in this study. Stability of the chronic kidney disease more than 30 days.
Exclusion criteria
Exclusion criteria: Patients who do not perform all stages of the study. Presence of acute myocardial infarction in the last 3 months. An active inflammatory or infectious process. Decompensated coronary artery disease. Implantable kidney transplant candidate with live donor expected to undergo transplantation in the next 4 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum oxygen consumption after 12 weeks of combined training (aerobic and strength), assessed by the cardiopulmonary exercise test | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical activity level after 12 weeks of combined training, evaluated by the pedometer. Submaximal exercise capacity after 12 weeks of combined training, assessed by the 6-minute walk test. Physical activity in daily life activities after 12 weeks of combined training, assessed by the International Physical Activity Questionnaire (IPAQ). Quality of life after 12 weeks of combined training, assessed by the Kidney Disease Quality of Life Short Form questionnaire (KDQOL-SFTM). Muscle strength of the lower limbs after 12 weeks of combined training, assessed by the maximum repetition of quadriceps test. Pulmonary function after 12 weeks of combined training, assessed by spirometry. Respiratory muscle strength after 12 weeks of combined training, assessed by manovacuometry. Inflammatory profile, after 12 weeks of combined training, assessed by Interleukin-6 (IL-6), Alpha Tumor Necrosis Factor and C-Reactive Protein (CRP). Muscle strength and muscle endurance after 12 weeks of combined training, assessed by the sit-up test | — |
Countries
Brazil
Contacts
Public ContactFrancini;Paula Porcher Andrade;Eidt Rovedder
Hospital de Clínicas de Porto Alegre - HCPA / UFRGS;Universidade Federal do Rio Grande do Sul - UFRGS
Outcome results
None listed