Overweight
Conditions
Interventions
This is a pragmatic, randomized, controlled, three-arm, double-blind clinical trial in which the investigators responsible for assessments and data analysis will be blinded. Sixty adults of both sexes
Sponsors
Universidade Federal de São Carlos
Universidade Federal de São Carlos
Eligibility
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Both sexes; age between 18 and 40 years; classified as overweight or grade I or grade II obesity according to fat mass index measured by dual-energy x-ray absorptiometry; healthy adults without any chronic or acute disease and who started any physical activity in the previous 3 months.
Exclusion criteria
Exclusion criteria: Electrocardiographic alterations including ischemia, overloads, conduction disorders, and severe arrhythmias such as ventricular tachycardia; fat mass index below or equal to normal or above grade III obesity; initiation of any physical activity in the last three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate abdominal subcutaneous adipose tissue thickness after 10 intervention sessions, measured by ultrasound imaging at the supraumbilical and infraumbilical abdominal regions;To evaluate body composition after 10 intervention sessions, measured by Dual Energy X-ray Absorptiometry, including total fat mass, fat mass index, visceral fat, android fat and gynoid fat;To evaluate the serum metabolic profile after 10 intervention sessions, measured by venous blood collection and proton nuclear magnetic resonance;To evaluate serum glycerol release after the intervention, measured by venous blood collection before and after the combined therapy session and after high-intensity interval training | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate cardiovascular autonomic modulation after the intervention, measured by heart rate variability, arterial pressure variability, symbolic analysis and cross-spectral analysis including baroreflex-related cardiovascular control;To evaluate sleep quality after the intervention, measured by the Pittsburgh Sleep Quality Index;To evaluate anxiety and depression symptoms after the intervention, measured by the Hospital Anxiety and Depression Scale;To evaluate perceived stress after the intervention, measured by the Depression, Anxiety and Stress Scale 21;To evaluate body image concerns after the intervention, measured by the Body Shape Questionnaire;To evaluate biochemical blood variables after the intervention, including complete blood count, glycated hemoglobin, fasting glucose, C-reactive protein, total cholesterol, high-density lipoprotein, low-density lipoprotein and triglycerides;To evaluate anthropometric and perimetry measurements after the intervention, including waist circumference, waist-to-hip ratio, waist-to-height ratio and neck circumference | — |
Countries
BR
Contacts
Public ContactAna Carolina Marcondes Scalli
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Outcome results
None listed