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Clinical study of Toothpaste with bioactives from the sap of the Amazonian dragon's blood tree (Croton lechleri) and Activated charcoal: sensory properties and effects on Bacterial plaque and Gingival health

Clinical study of Toothpaste with Dragon´s blood (Croton lechleri) and Actived charcoal: organoleptic properties and effects on Dental biofilm and Gingival health

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
REBEC
Registry ID
RBR-4x9pk3m
Enrollment
Unknown
Registered
2024-12-20
Start date
2023-04-03
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Toothbrushing

Interventions

Each participant will receive a standard opaque tube with dentifrice, without an obvious commercial brand, ensuring that the volunteer and the clinical examiner do not know the therapy used (double bl
only the general researcher will know their coding and will maintain confidentiality until the end of the study. Group 1 (experimental): 20 healthy volunteers, who will continuously use for 1 month co

Sponsors

Universidade Estadual Vale do Acaraú
Lead Sponsor
Universidade Federal do Ceará
Collaborator

Eligibility

Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Spontaneous demand; screening between April 2023 and April 2024; adults between 18 and 40 years old; both sexes; all ethnicities; without compromising systemic health; no smoking or alcohol consumption; dentition with more than 24 teeth; no ongoing orthodontic treatment; no daily use of mouthwashes; no use of mouthwashes and/or toothpastes with chlorhexidine in the last 60 days

Exclusion criteria

Exclusion criteria: Failure to sign the informed consent form (ICF); dropping out of the study; inappropriate use of the products to be tested; motor incoordination that makes tooth brushing difficult; surgery on the face or mouth that makes tooth brushing difficult

Design outcomes

Primary

MeasureTime frame
This study will be able to elucidate whether the use of commercial dentifrice with dragon's blood and activated charcoal is capable of offering sensory (organoleptic) or therapeutic advantages on dental biofilm and gingival health in healthy patients compared to commercial dentifrices without such compositions.

Secondary

MeasureTime frame
No secondary outcomes are expected.

Countries

Brazil

Contacts

Public ContactIgor Iuco Silva

Universidade Federal do Ceará

igor.iuco@sobral.ufc.br+55 (88) 99837-3015

Outcome results

None listed

Source: REBEC (via WHO ICTRP)