apnea of newborn
Conditions
Interventions
This is a prospective, observational, longitudinal study of the pre- and post-intervention at a tertiary-level neonatal Intensive Care Unit This study aims to analyze the effect of the loading dose o
Sponsors
Hospital Israelita Albert Einstein
Hospital Israelita Albert Einstein
Eligibility
Age
27 Weeks to No maximum
Inclusion criteria
Inclusion criteria: Newborns; of both genders; preterm newborns with gestational age equal to or less than 28 weeks; newborns between 28 and 32 weeks of gestational age under invasive or non-invasive ventilatory support; newborns with clinical diagnosis of apnea with gestacional age less than 37 weeks
Exclusion criteria
Exclusion criteria: Patients with major congenital malformations; anomalies of the upper digestive tract; primary neurological or drug-related abnormalities; newborns under high-frequency mechanical ventilation
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 1: It is expected to find a reduction in episodes of respiratory pauses, measured in breaths per minute,after administration of caffeine citrate in preterm newborns;Outcome found 2: We demonstrated a reduction in respiratory pauses, measured in breaths per minute, after administration of caffeine citrate in preterm newborns | — |
Primary
| Measure | Time frame |
|---|---|
| Expected Outcome 1: It is expected to find an increase in diaphragmatic electrical activity, measured in microvolts, after the loading dose of caffeine citrate, in preterm newborns;Outcome found 1: We demonstrated an increase in the electrical activity of the diaphragm, measured in microvolts, after administration of a loading dose of caffeine in preterm newborns | — |
Countries
Brazil
Contacts
Public ContactTatiana Zidan
Hospital Israelita Albert Einstein
Outcome results
None listed