Effects of supplementation with beneficial bacteria on quality of life, inflammatory profile, eating behavior, metabolism and nutritional status of patients after stomach reduction surgery

Effects of supplementation with probiotics on quality of life, eating behavior, inflammatory, metabolic and nutritional profile of patients in the postoperative period of gastric bypass in Roux-en-Y: a randomized, double-blind study

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

REBEC

Registry ID

RBR-4x3gqp

Enrollment

Unknown

Registered

2018-07-02

Start date

2018-04-16

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

Patients who meet the inclusion criteria will be added on a specific worksheet by the attending physician. Afterwards, randomization of patients in both groups (placebo and probiotic). It is estimated

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Eligibility

Age

18 Years to 59 Years

Inclusion criteria

Inclusion criteria: Adult inclusion criteria (18 - 59 years); both sexes; with a BMI equal to or greater than 35 kg / m2; submitted to the Roux-en-Y gastric bypass; without immediate surgical complications; who signed the TCLE

Exclusion criteria

Exclusion criteria: Patients submitted to other surgical techniques; patients who are undergoing reoperation or correction; patients who used antibiotics during the study period or who did not make adequate use of the placebo / probiotic

Design outcomes

Primary

Measure	Time frame
The group of individuals supplemented daily with probiotics for 12 weeks will present improvement in quality of life and symptoms with bacterial overgrowth and fecal excretion of fats. In addition, it will present a more significant than the placebo group in relation to the metabolic variables, inflammatory profile, behavior and food addiction.	—

Secondary

Measure	Time frame
Individuals with a diet rich in polysaccharides and low in lipids will present better results in the analyzed variables;Individuals in the intervention group with probiotics will present a better late-feeding behavior profile, presenting lower consumption of vicious foods	—

Countries

Brazil

Contacts

Public ContactMarília Zaparolli

Universidade Federal do Paraná

mariliazaparolli@gmail.com+55-041-996876677

Outcome results

None listed

Source: REBEC (via WHO ICTRP)