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Rhinoplasty in patients with Cleft Lip Palate

Rhinoseptoplasty in Cleft Lip Palate patients, prospective evaluation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4wyfw3k
Enrollment
Unknown
Registered
2023-11-27
Start date
2017-05-17
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cleft lip

Interventions

2. Access to the nasal septum, following septoplasty and removal of cartilaginous graft
This is a prospective study, in which 18 patients were evaluated and stratified using photographs, quality of life questionnaires and computed tomography (CT), with data collection carried out in two
3. Treatment of the back when necessary, with resection or scaling of the bony back and extra mucosal resection of the cartilaginous back in the presence of a hump, lateral osteotomies to correct late
4. Repositioning of the lower lateral cartilages 5. Chondromucosal (V-Y) flap of the lower lateral cartilages and underlying mucosa, if necessary
6. Partial resection of the lower lateral cartilages and symmetrization, when asymmetrical or very enlarged
and 7. Use of sutures and cartilaginous grafts to support and shape the nasal
E02.218.755

Sponsors

Hospital das Clinicas da Faculdade de Medicina de São Paulo
Lead Sponsor
Hospital das Clinicas da Faculdade de Medicina de São Paulo
Collaborator

Eligibility

Age
16 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients of both sexes; aged between 16 and 60 years; with unilateral non-syndromic cleft lip; who have already undergone primary cheiloplasty using known techniques; alveolar bone grafting

Exclusion criteria

Exclusion criteria: Age under 16 years old or over 60 years old; bilateral cleft lip; previously submitted to secondary rhinoseptoplasty; and those who did not have treated cleft lip and palate

Design outcomes

Primary

MeasureTime frame
Outcome found 1: Participated in the study 18 patients with cleft lip and palate, who underwent secondary structured rhinoseptoplasty. Of this total, n=12 (67%) received rib cartilage and n=6 (33%) septal cartilage. The computed tomography (CT) examination revealed a significant change in linear measurements, with a significant reduction in L1 (Distance from the pronasale point [pn] to the midpoint of the interpupillary line [mipl]), transverse measurement of the nostril on the cleft side and nasal width on the postoperative period, in addition to an increase in L5 (Distance from the point alare laterale [al] on the non-cleft side to the midpoint of the face [mpl] in the anterior view), L8 (Distance from the point al on the non-cleft side to the point pn on the inferior vision) and L11 (Distance from the subnasale point to the pn point in the inferior vision) in the same period. Photogrammetry also revealed a significant increase in L5, L11 (mm) and reduction in transverse measurements of the nostrils on the cleft (LF) and non-cleft side (LNF) (mm). The ratios evaluated were not statistically significant when comparing the two imaging methods separately. However, the two methodologies compared showed that both pre-operatively (L2, L3, transverse measurement of the LF and LNF nostrils) and post-operatively (L1, L2, L3, L4 and transverse measurement of the LF and LNF nostrils), some measurements were different (p<0.05). The use of rib cartilage showed an increase in the volume of the nose divided in half LF, the rise of the tip and the back in relation to the use of a septum. The LF/LNF ratio for the airway showed an improvement in symmetry in the postoperative rib surgery ( 0.98±0.26) compared to pre (0.79±0.19; p=0.027) by photogrammetry and CT. Also for those who received rib cartilage, there was an improvement in postoperative symmetry for the LF/LNF ratio of the sinuous nose (0.99±0.11) compared to pre-operative (0.97±0.12; p=0.004) by CT. When comparing the meth

Secondary

MeasureTime frame
No secondary outcomes were expected

Countries

Brazil

Contacts

Public ContactAlex Fioravanti

Hospital das Clinicas da Faculdade de Medicina de São Paulo

dralex@clinicafioravanti.com.br+55(11)26610000

Outcome results

None listed

Source: REBEC (via WHO ICTRP)