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Can whole-body exercises reduce pain and improve function in people with knee Osteoarthritis?

Can non-localized exercises reduce pain and improve function in people with knee Osteoarthritis? a randomized blinded clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4wvb8bn
Enrollment
70
Registered
2026-06-22
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis Join Diseases

Interventions

This study is a blinded, randomized clinical trial with a total duration of 12 weeks for both protocols, of which 8 weeks are allocated to the treatment protocol involving exercise performance. Follow

Sponsors

Universidade Federal de Santa Catarina
Lead Sponsor
Universidade Federal de Santa Catarina
Collaborator

Eligibility

Age
45 Years to No maximum

Inclusion criteria

Inclusion criteria: The study will include individuals who have had osteoarthritis for at least 6 months; who experience movement-related join pain; morning stiffness lasting less than 30 minutes; the presence of crepitus or limited range of motion

Exclusion criteria

Exclusion criteria: Participants will be excluded if they have injuries to the upper or lower limbs that would prevent them from completing the proposed training; a history of orthopedic surgery within the past 12 months; patients with lower limb arthroplasty; pregnancy; inability to follow instructions or complete the questionnaire; individuals in the active phase of sistemic complications relates to other rheumatic diseases; severe cardiovascular disease; uncontrolled hypertension; cancer that limits participation in the protocol; participants who regularly engage in physical exercise at other locations or those already undergoing non-pharmacological treatment

Design outcomes

Primary

MeasureTime frame
It is expected that patients will report a reduction in knee pain, as measured by the Numerical Pain Rating Scale (NRS)

Secondary

MeasureTime frame
It is expected that an improvement in quality of life will be observed using the Knee Injury and Osteoarthritis Outcome Store;It is expected that improvements will be observed in measures of functional ability, as assessed by the 30 second Chair Stand Test (30CST), Timed Up and Go (TUG), and 10 Meter Walk Test (10MWT);Assess medication use using a medication diary compiled by the study author;Assess maximum isometric strength using a handheld dynamometer

Countries

BR

Contacts

Public ContactMaria Clara Oliveira

Universidade Federal de Santa Catarina

maria.clara.lima@posgrad.ufsc.br+554837216255

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Aug 10, 2026