Non-alcoholic fatty liver disease (NAFLD)
Conditions
Interventions
This is a two-arm randomized controlled clinical study. No blinding. Patients from both groups are already routinely treated at the Hepatic Steatosis Outpatient Clinic at Hospital de Clínicas and refe
Sponsors
Universidade Federal do Paraná.
Complexo Hospital de Clínicas da Universidade Federal do Paraná
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients must be over 18 years of age; must not be significant drinkers; and this self-reported questioning is foreseen in the nutritionist consultation protocol. Alcohol consumption is considered significant if defined as > 21 drinks per week in men and > 14 drinks per week in women in a two-year period prior to baseline liver histology
Exclusion criteria
Exclusion criteria: Patients with positive serology for hepatitis B and C and HIV will be excluded from the study; patients with disabsorptive diseases (Chron's Disease, Celiac Disease); with chronic kidney disease; who are on the waiting list for bariatric surgery; pregnant and lactating women. People using steatogenic drugs or with hereditary liver diseases or who are not able to answer the nutritional literacy questionnaire with or without the help of the researcher or even patients who report frequent alcoholic intake will also be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a difference in body weight with weight loss of 5% to 10% of body weight and reduction in centripetal adipose mass with a reduction in waist measurement | — |
Secondary
| Measure | Time frame |
|---|---|
| Cessation of NAFLD progression is expected by means of liver enzymes; improvement in the cure prognosis of Non-Alcoholic Fatty Liver Disease (NAFLD); weight loss continuity; improvement in consumption pattern; self-reported quality of life improvement | — |
Countries
Brazil
Contacts
Public ContactSilvia Spinelli
Universidade Federal do Paraná.
Outcome results
None listed